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Mosaic analysis has demonstrated that Notch is required cell-autonomously for stalk cell specification by actively repressing tip cell phenotypes [ Last edited by cainiaodui on 2013-8-29 at 14:13 ] |
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cainiaodui: 金幣+5, 翻譯EPI+1 2013-08-29 21:18:17
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嵌合分析實(shí)驗(yàn)表明柄細(xì)胞自主特化的過程中需要Notch信號途徑來積極地抑制尖細(xì)胞表現(xiàn)型 補(bǔ)充： ；嵌合分析 Mosaic analysis https://www.eoechina.com.cn/notice-details-3794.html https://www.ebiotrade.com/newsf/2011-8/2011811113335482.htm https://www.ebioservice.com/show_news.asp?id=1367 ；表現(xiàn)型 =表型=phentype ；phenotype, phenotype all the observable characteristics of an organism, such as shape, size, colour, and behaviour, that result from the interaction of its genotype基因型 (total genetic inheritance) with the environment. The common type of a group of physically similar organisms is sometimes also known as the phenotype. The phenotype may change constantly throughout the life of an individual because of environmental changes and the physiological and morphological changes associated with aging. Different environments can influence the development of inherited traits (as size, for example, is affected by available food supply) and alter expression by similar genotypes (for example, twins maturing in ... (100 of 142 words) ；cell autonomously 細(xì)胞自主 https://www.nibs.ac.cn/index.php?act=view&id=2786 ；尖端細(xì)胞 (tip cell)和 柄細(xì)胞 (stalk cell) https://cjbmb.bjmu.edu.cn/CN/abstract/abstract19392.shtml ；DLL4/Notch信號通路在腫瘤血管芽生過程中作用研究進(jìn)展 ；（de facto，拉丁語，指雖法律上站不住，但事實(shí)上卻為人所承認(rèn)） https://www.ebiotrade.com/newsf/2008-8/200884153107.htm ；血管內(nèi)皮生長因子（英文：vascular endothelial growth factor，簡稱：VEGF），早期亦稱作血管通透因子（英文： vascular permeability factor，簡稱：VPF)，是對血管內(nèi)皮細(xì)胞具有特異性的肝素結(jié)合生長因子（heparin-binding growth factor），可在體內(nèi)誘導(dǎo)血管新生（induce angiogenesis in vivo）。 https://zh.wikipedia.org/zh-cn/% ... F%E5%9B%A0%E5%AD%90 ；Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that stimulates vasculogenesis and angiogenesis血管發(fā)生和發(fā)展. It is part of the system that restores the oxygen supply to tissues when blood circulation is inadequate. Serum concentration of VEGF is high in bronchial asthma and low in diabetes mellitus. VEGF's normal function is to create new blood vessels during embryonic development, new blood vessels after injury, muscle following exercise, and new vessels (collateral circulation) to bypass blocked vessels ；Vasculogenesis and Angiogenesis Vasculogenesis is the process of new blood vessel formation during embryonic development of the cardiovascular system. This is followed by formation of a vascular tree and finally the cardiovascular system with the myriad of blood essels that nourish all tissues and organs. Angiogenesis, on the other hand is the process by which new blood vessels take shape from existing blood vessels by "sprouting" of endothelial cells thus expanding the vascular tree. Both scenarios are based on activation, migration, proliferation and maturation of unique precursor cells. https://www.intechopen.com/books ... generative-medicine 在多種細(xì)胞的特化（specification）中起關(guān)鍵作用的傳導(dǎo)細(xì)胞間相互作用信號的途徑, 稱為Notch信號途徑[1] https://baike.baidu.com/view/575908.htm https://www.dls.ym.edu.tw/lesson3/org1.htm Notch 信號途徑的字面意思；Notch基因最早發(fā)現(xiàn)于果蠅，部分功能缺失導(dǎo)致翅緣缺刻（notches）。 https://www.baike.com/wiki/Notch ... 7%E9%80%94%E5%BE%84 |
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