 |
 |
 |
 |
 |
 |
||
 |
 |
 |
 |
 |
| 3 | 1/1 | 返回列表 |
| 查看: 455 | 回復(fù): 2 | ||
愛如風(fēng)過3610金蟲 (正式寫手)
|
[求助]
幫忙翻譯一段話，謝謝
|
| In summary, the data presented here indicate that protein robustness and adaptability can be explained through a model in which the main functional constraints are loaded in the sector—a sparse, collectively evolving network within the protein structure. By saturation point mutagenesis, we find that sector positions selectively resist variation when challenged with wild-type ligand, but can flip to promote variation when challenged with a functionally distinct ligand. This epistatic coupling between ligand and sector underlies efficient functional adaptation, permitting considerable changes in specificity through very few mutations. Turned around, these data provide support for the hypothesis that the sector architecture might be the natural solution to design by evolution under conditions of constantly fluctuating environments. Such environments impose the need for maintaining robustness to mutation and adaptability to varying selection pressures and have been shown theoretically to influence the design of evolving systems. It will be important to now experimentally test the notion that the statistical history of fluctuations in conditions of selection fundamentally defines the physical design of natural proteins. |
回復(fù)此樓» 猜你喜歡
求調(diào)劑
已經(jīng)有3人回復(fù)
-
265求調(diào)劑
已經(jīng)有4人回復(fù)
-
085700資源與環(huán)境308求調(diào)劑
已經(jīng)有6人回復(fù)
-
一志愿吉林大學(xué)材料學(xué)碩321求調(diào)劑
已經(jīng)有12人回復(fù)
-
286分人工智能專業(yè)請求調(diào)劑愿意跨考！
已經(jīng)有3人回復(fù)
-
329求調(diào)劑
已經(jīng)有5人回復(fù)
-
申請回稿延期一個月，編輯同意了。但系統(tǒng)上的時間沒變，給編輯又寫郵件了，沒回復(fù)
已經(jīng)有4人回復(fù)
-
材料學(xué)碩318求調(diào)劑
已經(jīng)有5人回復(fù)
-
一志愿中國海洋大學(xué)，生物學(xué)，301分，求調(diào)劑
已經(jīng)有6人回復(fù)
-
081700化工學(xué)碩調(diào)劑
已經(jīng)有3人回復(fù)
zhenwuhuang
至尊木蟲 (文學(xué)泰斗)
- 翻譯EPI: 4
- 應(yīng)助: 4351 (副教授)
- 金幣: 10192.3
- 散金: 1
- 紅花: 137
- 帖子: 65925
- 在線: 2433.9小時
- 蟲號: 2227382
- 注冊: 2013-01-07
- 性別: GG
- 專業(yè): 人類營養(yǎng)
2樓2015-08-23 16:36:17
愛如風(fēng)過3610
金蟲 (正式寫手)
- 應(yīng)助: 6 (幼兒園)
- 金幣: 750.6
- 散金: 497
- 紅花: 2
- 帖子: 311
- 在線: 575.2小時
- 蟲號: 1614838
- 注冊: 2012-02-13
- 性別: GG
- 專業(yè): 蛋白質(zhì)組學(xué)
3樓2015-08-23 16:49:58
相關(guān)版塊跳轉(zhuǎn)
我要訂閱樓主 愛如風(fēng)過3610 的主題更新
| 3 | 1/1 | 返回列表 |
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 307求調(diào)劑 +9 | 冷笙123 2026-03-17 | 9/450 |
|
|---|---|---|---|---|
|
[考研] 一志愿武漢理工材料工程專碩調(diào)劑 +5 | Doleres 2026-03-19 | 5/250 |
|
|
|
[考研] 一志愿南京理工大學(xué)085701資源與環(huán)境302分求調(diào)劑 +3 | 葵梓衛(wèi)隊 2026-03-18 | 5/250 |
|
|
|
[考研] 321求調(diào)劑 +8 | 何潤采123 2026-03-18 | 10/500 |
|
|
|
[考研] 能源材料化學(xué)課題組招收碩士研究生8-10名 +4 | 脫穎而出 2026-03-16 | 12/600 |
|
|
|
[考研] 材料專碩英一數(shù)二306 +5 | z1z2z3879 2026-03-18 | 5/250 |
|
|
|
[考研] 【同濟軟件】軟件（085405）考研求調(diào)劑 +3 | 2026eternal 2026-03-18 | 3/150 |
|
|
|
[考研] 311求調(diào)劑 +11 | 冬十三 2026-03-15 | 12/600 |
|
|
|
[考研] 297求調(diào)劑 +8 | 戲精丹丹丹 2026-03-17 | 8/400 |
|
|
|
[考研] 312求調(diào)劑 +8 | 陌宸希 2026-03-16 | 9/450 |
|
|
|
[考研] 277調(diào)劑 +5 | 自由煎餅果子 2026-03-16 | 6/300 |
|
|
|
[考研] 考研化學(xué)學(xué)碩調(diào)劑，一志愿985 +4 | 張vvvv 2026-03-15 | 6/300 |
|
|
|
[考研] 085601求調(diào)劑 +4 | Du.11 2026-03-16 | 4/200 |
|
|
|
[考研] 283求調(diào)劑 +3 | 聽風(fēng)就是雨； 2026-03-16 | 3/150 |
|
|
|
[考研] 藥學(xué)383 求調(diào)劑 +3 | 藥學(xué)chy 2026-03-15 | 4/200 |
|
|
|
[考研] 304求調(diào)劑 +4 | ahbd 2026-03-14 | 4/200 |
|
|
|
[考研] 304求調(diào)劑 +3 | 曼殊2266 2026-03-14 | 3/150 |
|
|
|
[考研] 085601材料工程315分求調(diào)劑 +3 | yang_0104 2026-03-15 | 3/150 |
|
|
|
[考研] 289求調(diào)劑 +4 | 這么名字咋樣 2026-03-14 | 6/300 |
|
|
|
[考研] 290求調(diào)劑 +3 | ADT 2026-03-13 | 3/150 |
|