法國巴黎綜合理工大學招聘博士后
如題,
Bastien Nay 研究員課題組,明年一月份去巴黎綜合理工大學(歐洲最好的理工大學之一)上任,現(xiàn)需要博士生和博士后,有意向請直接聯(lián)系Bastien Nay研究員或通過我推薦。(今年的CSC博士生1月初申請截止,博士后2月申請截止)
另我有招生簡章,可是上傳出現(xiàn)亂碼,有意者盡快發(fā)簡歷!
課題組鏈接:
https://naygroup.wordpress.com/
我的郵箱:lxwlxw1234@163.com
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今日熱帖
京公網(wǎng)安備 11010802022153號
這個對專業(yè)有要求嗎
不是這個方向的 好地方
有機化學,藥物化學或化學生物學,不好意思沒有寫明!
有機化學,藥物化學或化學生物學,不好意思沒有寫明!
Research Topic for the ParisTech/CSC PhD Program
Subfield: Organic chemistry
ParisTech School: Ecole Polytechnique
Title: Combining biomimetic and diversity-oriented strategies to synthesize natural products and medicinally relevant analogues in the aurachin series
Advisor(s):
Dr. Bastien Nay, bastien.nay@polytechnique.edu, https://naygroup.wordpress.com/
Short description of possible research topics for a PhD:
In 2013 we described the first total synthesis of aurachin D and analogues, and found potent inhibitory properties on the mitochondrial respiratory chain.1 Based on Müller's biosynthetic hypotheses, we also investigated the reactivity of our aurachin analogues in the presence of one of the aurachin biosynthetic enzymes, leading to new biosynthetic hypotheses involving a cascade of retro-[2,3]Wittig and Claisen rearrangements instead of the originally suggested pinacol rearrangement.2 Based on these findings, this PhD project aims at developing bio-inspired strategies to synthesize aurachins B and C. Diversity-oriented and function-oriented strategies will be applied in order to (1) build a medicinally relevant library of compounds and test it on relevant biological targets, and (2) simplify the aurachin core to the essential elements for biological activities (e.g. a shorter geranyl derivative has the same activity as the original farnesyl). In addition, a final level of diversity (and complexity) will be obtained through bio-inspired photooxygenated processes currently developed in our group. Overall the methodological aspects of organic synthesis will gain from our biosynthetic hypothesis to be synthetically challenged, since unprecedented chemical rearrangements (i.e. retro-[2,3]Wittig) with potentially high impact are expected to be unveiled by this work.
Required background of the student: The PhD applicant should have a Master degree in organic chemistry and a strong interest in organic synthesis and synthetic methodologies. A high level of spoken and written English is also expected. An interest in biosynthetic pathways and chemical biology would be appreciated
,
剛回復你的是博士生,博士后就是有機化學和藥物化學!
具體你可以和Bastien Nay教授直接聯(lián)系詢問,附上你的簡歷!也可以先把簡歷給我看看把把關,推薦一下!