劉 會(huì) 博士，副教授，碩士生導(dǎo)師
       化學(xué)系主任
首批“山東省優(yōu)青”(2015)，
首批“山東省高等學(xué)校青年創(chuàng)新團(tuán)隊(duì)人才
引育計(jì)劃(2019)”
山東理工大學(xué)“雙百工程”人才

【聯(lián)系方式】
山東理工大學(xué) 化學(xué)工程學(xué)院
辦公地點(diǎn)：山東理工大學(xué)西校區(qū)4號(hào)實(shí)驗(yàn)樓411室
通訊地址：山東省淄博市張店區(qū)張周路12號(hào)山東理工大學(xué)化工學(xué)院
ORCID ID：https://orcid.org/0000-0001-8916-6055
電子郵箱：huiliu1030@sdut.edu.cn, huiliu1030@163.com
郵編：255049

【教育與科研經(jīng)歷】
2016.12-2017.12，法國(guó)原子能委員會(huì)(CEA)，藥物化學(xué)，訪問(wèn)學(xué)者，導(dǎo)師：Frederic Taran教授
2016.1-至今，山東理工大學(xué)化學(xué)工程學(xué)院，副教授
2013.11-2014.11，法國(guó)原子能委員會(huì)(CEA)和牛津大學(xué)，有機(jī)化學(xué)，博士后，導(dǎo)師：Frederic Taran教授和Véronique Gouverneur教授
2013.10-2015.12，山東理工大學(xué)化學(xué)工程學(xué)院，講師
2012.3-2013.11，華東師范大學(xué)綠色化學(xué)與化工過(guò)程綠色化重點(diǎn)實(shí)驗(yàn)室，有機(jī)化學(xué)，博士后，導(dǎo)師：姜雪峰研究員
2009.5-2010.4，美國(guó)GlaxoSmithKline (葛蘭素史克)  研發(fā)部，訪問(wèn)學(xué)者
2006.9-2012.3，華東理工大學(xué)精細(xì)化工研究所，應(yīng)用化學(xué)，博士，導(dǎo)師：童曉峰教授和王利民教授
2002.9-2006.7，曲阜師范大學(xué)化學(xué)與化工學(xué)院，學(xué)士。

【研究方向】
1. 金屬導(dǎo)向的有機(jī)合成方法學(xué)研究
2. 18F,13C標(biāo)記的PET藥物研發(fā)以及在醫(yī)藥領(lǐng)域中的創(chuàng)新應(yīng)用
3. 精細(xì)化工產(chǎn)品和醫(yī)藥中間體的合成路線以及合成工藝的研發(fā)

【主持的科研項(xiàng)目】
11. 鈀-自由基協(xié)同接力催化精準(zhǔn)構(gòu)筑Csp3-Csp3鍵及其機(jī)理研究，國(guó)家自然科學(xué)基金面上基金，22078178，2021.01-2024.12

10. 過(guò)氧化酯類系列引發(fā)劑清潔生產(chǎn)新工藝研發(fā)，新舊動(dòng)能轉(zhuǎn)換重大工程重大課題攻關(guān)，2019.04-2021.04 (第三參與人)
9. 鈀催化還原偶聯(lián)構(gòu)建Csp2-Csp3 鍵反應(yīng)的研究及其在天然產(chǎn)物全合成中的應(yīng)用，國(guó)家自然科學(xué)基金青年基金，21302057, 2014.01-2016.12
8. 鈀催化非活化烷基鹵代烴構(gòu)建Csp2-Csp3鍵的偶聯(lián)反應(yīng)方法學(xué)及其機(jī)理研究，山東省屬高校優(yōu)秀青年基金，ZR2015JL005，2015.07-2016.12
7. 非活化Csp3-Csp3鍵綠色化構(gòu)建方法研究，山東省自然科學(xué)基金面上基金，ZR2018MB008, 2018.03-2021.06
6. 鈀催化非活化烷基鹵代烴構(gòu)建碳碳鍵反應(yīng)方法學(xué)研究，中國(guó)博士后面上基金一等資助，2016M590736
5.基于Ramberg-Bäcklund反應(yīng)策略的天然產(chǎn)物全合成，中國(guó)博士后面上基金二等資助： 2012M520858
4.鈀催化非活化烷基鹵代烴構(gòu)建碳碳鍵反應(yīng)方法學(xué)研究，山東省博士后創(chuàng)新項(xiàng)目專項(xiàng)資金一等資助，201501002
3.中央高�；�本科研業(yè)務(wù)費(fèi)專項(xiàng)資金（華東師范大學(xué)）
2.山東理工大學(xué)青年教師發(fā)展支持計(jì)劃
1.山東理工大學(xué)博士啟動(dòng)基金，2013

【教改項(xiàng)目】
1.        山東理工大學(xué)實(shí)驗(yàn)教學(xué)卓越計(jì)劃-苯丙炔醇的制備，2016
2.        山東理工大學(xué)研究生導(dǎo)師指導(dǎo)能力提升項(xiàng)目-研究生教育國(guó)際化研究與實(shí)踐，2018
3.        山東理工大學(xué)課程綜合改革項(xiàng)目-精細(xì)有機(jī)合成，2018
4.        新工科視角下化學(xué)多元化、創(chuàng)新型人才培養(yǎng)模式探索，2020
【獲獎(jiǎng)情況】
山東理工大學(xué)“師德標(biāo)兵”（2020）
山東省自然科學(xué)獎(jiǎng)三等獎(jiǎng)-磁性、催化功能分子材料體系的構(gòu)筑及結(jié)構(gòu)性質(zhì)研究（2019）
第十六屆挑戰(zhàn)杯 魯南制藥 山東省大學(xué)生課外學(xué)術(shù)科技作品競(jìng)賽二等獎(jiǎng)（2019）
山東理工大學(xué)“優(yōu)秀教師”（2019）
山東理工大學(xué)教學(xué)質(zhì)量獎(jiǎng)（2018）
第十五屆“挑戰(zhàn)杯”聯(lián)興科技課外學(xué)術(shù)科技作品優(yōu)秀指導(dǎo)教師（2017）
淄博市科學(xué)技術(shù)三等獎(jiǎng)（2017）
上海市優(yōu)秀畢業(yè)生(2012)
天鼎-東岳特等獎(jiǎng)學(xué)金(2011)
華東理工大學(xué)高水平文章獎(jiǎng)學(xué)金(2011)
山東省優(yōu)秀畢業(yè)生(2006)
山東省優(yōu)秀學(xué)生(2003)

【發(fā)表論文】
2021
48. J. Li, Y. Yang, Y. Liu, Q. Liu, L. Zhang, X. Li, Y. Dong, and H. Liu*. Palladium/Norbornene Catalyzed ortho Amination/Cyclization of Aryl Iodide: Process to 3-Methyl-Indole Derivates and Controlla-ble Reductive Elimination against the Second Amination. Org. Lett., 2021, accepted.
47. X. Sun, X. Dong, H. Liu* and Y. Liu*. Recent Progress in Palladium-Catalyzed Radical Reactions. Adv. Synth. Catal. 2021, 363, xxxx. (DOI: 10.1002/adsc.202001315)
47. X. Sun, D. Xu, Y. Yang, J. Fu, Y. Wang, Z. Li, Y. Liu  and  H. Liu. Palladium-Catalyzed Cascade 5-Exo-Trig Radical Cyclization/Aromatic C-H Alkylation with Unactivated Alkyl Iodides. Org. Bio. Chem., 2021, DOI: 10.1039/D1OB00346A.
46. C. Cao, Y. Yang, X. Li, Y. Liu, H. Liu,* Z. Zhao,* and L. Chen*. Pd-Catalyzed Cascade Metallo-Ene Cyclization/Metallo-Carbene Coupling of Allenamides. Eur. J. Org. Chem. 2021, xxxx. (DOI:10.1002/ejoc.202001625)
2020
45. J. Li, L. Meng, Q. Liu, X. Du, L.-P. Xu, L. Zhang, F.-G. Sun, X. Li, D. Zhang, X. Xiao and H. Liu*. Palladium-Catalyzed Intramolecular Aerobic Alkenylhydroxylation of Allenamides with Alkenyl Iodides. Org. Chem. Front., 2020, 7, 3880-3886.
44. X. Dong, H. Wang, H. Liu* and F. Wang*. Recent Advanced on Transition Metal Migration Involved Reactions. Org. Chem. Front., 2020, 7, 3530-3556.

2019年
43. M. Richard, C. Truillet, V.-L. Tran, H. Liu, K. Porte, D. Audisio, M. Roche, B. Jego, S. Cholet, F. Fenaille, B. Kuhnast, F. Taran* and S. Specklin. New fluorine-18 pretargeting PET imaging by Q2 bioorthogonal chlorosydnone–cycloalkyne click reaction. Chem. Commun., 2019, 55, 10400-10403
42. L. Meng, X. Chi, X. Sun, C. Cao, B. Ai, Q. Liu, P. Zhao, Z. Zhao, Y. Dong* and H. Liu*. An organocatalytic method for constructing pyrroles via the cycloisomerisation of Z-1-iodo-4-N-methylbenzenesulfonyl-1,6-enynes. Org. Biomol. Chem., 2019, 17, 7669-7673.
41. X. Chi, L. Meng, X. Sun, Q. Liu, B. Ai, L. Chen, D. Zhang, P. Zhao, Y. Dong, H. Liu.* Palladium-Catalyzed Cycloisomerization of (Z)-1-Iodo-1,6-dienes to 3-Aza-bicyclo[4.1.0]hept-2-enes. Asian J.Org. Chem. 2019, 8, 840-843.
40. J. Song, X. Chi, L. Meng, P. Zhao, F. Sun, D. Zhang, L. Jiao, Q. Liu, Y. Dong, and H. Liu.* Pd-Catalyzed Tandem Coupling Reaction of 2-gem-Dibromovinylanilines and N-Tosylhydrazones to Construct 2-(1-phenylvinyl)-indoles. Adv. Synth. Catal. 2019, 361, 3599-3604.
39. J. Cui, L. Meng, X. Chi, Q. Liu, P. Zhao, D. Zhang, L. Chen, X. Li, Y. Dong and H. Liu.* Palladium-Catalyzed Regiocontrollable Hydroarylation Reaction of Allenamides with B2pin2/H2O. Chem. Commun., 2019, 55, 4355 – 4358.
38. F. Yan, H. Liang, B. Ai, W. Liang, L. Jiao, S. Yao, P. Zhao, Q. Liu, Y. Dong, and H. Liu.* Palladium-Catalyzed Intermolecular [4 + 2] Formal Cycloaddition with (Z)-3-Iodo Allylic Nucleophiles and Allenamides. Org. Biomol. Chem., 2019, 17, 2651 - 2656.
2018年
37. J. Cui, J. Song, Q. Liu, H. Liu,* and Y. Dong.* Transition-Metal-Catalyzed Cyanation by Using an Electrophilic Cyanating Agent, N-Cyano-N-phenyl-p-toluenesulfonamide (NCTS). Chem. Asian J. 2018, 13, 482-495. (SCI二區(qū)IF = 4.083)
36. J. Li, X. Chi, L. Meng, L. Jiao, W. Shang, P. Wang, D. Zhang, Y. Dong, Q. Liu,* and H. Liu*. Palladium-Catalyzed Heck-Type Cascade Cyclization of (Z)-1-Iodo-1,6-dienes with N-Tosyl Hydrazones. Org. Biomol. Chem., 2018, 16, 7356-7360. (SCI二區(qū)) IF = 3.56
35. H. Liang, L. Meng, X. Chi, S. Yao, H. Chen, L. Jiao, Q. Liu, D. Zhang, H. Liu,* and Y. Dong*. Palladium/Copper Co-catalyzed Cascade Metallo-ene/Sonogashira Coupling Reaction of Allenamides. Asian J. Org. Chem., 2018, 7, 1793-1796. (SCI三區(qū)IF=2.788)
34. J. Song, J. Cui, H. Liang, Q. Liu, Y. Dong, and H. Liu*. Palladium-Catalyzed Direct Oxidative Esterification of Indoles at the C3 Position: A Novel Prospect for C(sp2)-H Acyloxylation. Asian J. Org. Chem., 2018, 7, 341-345. (SCI三區(qū)IF=2.788)
33. J. Song, Q. Liu, H. Liu,* and X. Jiang.* Recent Advances in Palladium-Catalyzed Carboxylation with CO2. Eur. J. Org. Chem., 2018, 6，696-713. (SCI三區(qū)IF= 2.834)
2017年
32. X. Dong, J. Cui, J. Song, Y. Han, Q. Liu, Y. Dong and Hui Liu*. Palladium-catalyzed intramolecular reductive olefin hydrocarbonation: benzylic hydrogen serving as a new hydrogen donor. Chem. Commun., 2017, 53, 4903-4906. (Front Cover, SCI一區(qū))
31. F. Yan, H. Liang, J. Song, J. Cui, Q. Liu, S. Liu, P. Wang, Y. Dong* and H. Liu*. Palladium-Catalyzed Cyclization-Heck Reaction of Allenamides: An Approach to 3-Methylene-5-phenyl-1,2,3,4-tetrahydropyridine Derivatives. Org. Lett., 2017, 19, 86-89. (SCI一區(qū))
30. H. Liang,  F. Yan,   X. Dong,   Q. Liu,   X. Wei,   S. Liu,   Y. Dong*,    H. Liu*. Palladium-Catalyzed Cascade Metallo-Ene/Suzuki Coupling Reaction of Allenamides. Chem. Commun., 2017, 53, 3138-3141. (SCI一區(qū))
29. J. Li, Y. Hu, D. Zhang, Q. Liu*, Y. Dong and H. Liu*. Transition-Metal- Catalyzed Reactions Involving Oximes. Adv. Synth. Catal., 2017, 359, 710-771. (SCI一區(qū))
28. X. Dong, Q. Liu*, Y. Dong and H. Liu*, Transition-Metal-Catalyzed Electrophilic Amination: Application of O-Benzoylhydroxylamines in the Construction of the C-N Bond. Chem. Eur. J., 2017, 23, 2481-2511. (Frontispiece, SCI二區(qū))
28. J. Cui, H. Wang, J. Song, X. Chi, L. Meng, Q. Liu, D. Zhang, Y. Dong and H. Liu*. Copper(I)-Catalyzed 5-exo-trig Radical Cyclization/Borylation of Alkyl Halides: Access to Functionalized Pyrrolidine Derivates. Org. Biomol. Chem., 2017, 15, 8508-8512. (SCI二區(qū)) IF = 3.56
27. X. Dong, Y. Hou, F. Meng, H-B. Liu and H. Liu*. Recent Advances on Alkyl-Heck Reaction. Chin. J. Org. Chem., 2017, 37, 1088-1098.(Invited Paper)
2016年
26. H. Liu, D. Audisio, L. Plougastel, E. Decuypere, V. Gouverneur, and F. Taran. Ultrafast Click Chemistry with Fluorosydnones. Angew. Chem. Int. Ed., 2016, 55, 12073-12077. (SCI一區(qū))
25. J. Li, W. Yang, F. Yan, Q. Liu, P. Wang, Y. Li, Y. Zhao, Y. Dong* and H. Liu*. Pd-Catalyzed Oxidative Isomerization of Propargylic Acetates: Highly Efficient Access to α-Acetoxyenones via Alkenyl Csp2-O Bond-Forming Reductive Elimination from PdIV. Chem.Comm., 2016, 52, 10644-10647. (SCI一區(qū))
24. X. Dong, Y. Han, F. Yan, Q. Liu*, P. Wang, K. Chen, Y. Li, Z. Zhao, Y. Dong, and H. Liu*. Palladium-Catalyzed 6‑Endo Selective Alkyl-Heck Reactions: Access to 5‑Phenyl-1,2,3,6-tetrahydropyridine Derivatives. Org. Lett., 2016, 18, 3774-3777. (SCI一區(qū))
23. H. Liang, H. Liu* and X. Jiang. Synlett, 2016, 27, 2774-2782. (Invited Paper)
2015年
22. Q. Liu, X. Dong, J. Li, J. Xiao, Y. Dong* and H. Liu*. Recent Advances on Palladium Radical Involved Reactions. ACS Catal., 2015, 5, 6111-6137. (Invited Review, SCI一區(qū))
21. E. Decuypere, S. Specklin, S. Gabillet, D. Audisio, H. Liu, L. Plougastel, S. Kolodych, F. Taran. Copper(I)-Catalyzed Cycloaddition of 4-Bromosydnones and Alkynes for the Regioselective Synthesis of 1,4,5-Trisubstituted Pyrazoles. Org. Lett., 2015, 17, 362-365. (SCI一區(qū))
2014年以前：
20. H. Liu, J. Wei, Z. Qiao, Y. Fu, X. Jiang*. Palladium-Catalyzed Intramolecular Reductive Cross-Coupling of Csp2-Csp3 Bond Formation. Chem. Eur. J., 2014, 20, 8308-8313. (SCI二區(qū)) IF=5.16
19. H. Liu, M. Feng, X. Jiang*. Unstrained Carbon-Carbon Bond Cleavage. Chem. Asian J., 2014, 9, 3360-3382. (SCI二區(qū))IF=3.7
18. H. Liu, X. Jiang        *. Pd-Catalyzed Reactions from Unactivated Csp3-I Bond. Pure and Applied Chemistry, 2014, 85, PAC.2014.5032. IF=4.7
17. Z. Qiao,§ H. Liu,§ X. Xiao, Y. Fu, J. Wei, Y. Li* and X. Jiang*. Efficient Access to 1, 4-Benzothiazine: Palladium-Catalyzed Double C-S Bond Formation Using Na2S2O3 as Sulfuration Reagent. Org. Lett., 2013‚ 15‚ 2594-2597. (SCI一區(qū))
16. H. Liu, Z. Gu and X. Jiang*. Direct Trifluoromethylation of C-H Bond. Adv. Synth. Catal., 2013, 355, 617-626. (SCI一區(qū))
15. H. Liu, Xuefeng Jiang*. Transfer of Sulfur: From Simple to Diverse. Chem. Asian J., 2013, 8, 2546-2563. (SCI二區(qū))
14. H. Liu, X. Jiang*. Mechanistic Insight to the Reaction Pathway of Aerobic Oxidative C-C Bond Cleavage of α-Hydroxy Ketones. Synlett, 2013, 24, 1311-1315.
13. L. Wang, J. Huang, S. Peng, H. Liu, X. Jiang* and J. Wang*. Palladium-Catalyzed Oxidative Cycloaddition via C–H/N–H Activation: Access to Benzazepines. Angew. Chem. Int. Ed., 2013, 52, 1768-1772. (SCI一區(qū))
12. H. Liu, C. Dong, Z. Zhang, P. Wu and X. Jiang*. Transition-Metal-Free Aerobic Oxidative Cleavage of C-C Bonds in α-Hydroxy Ketones and Mechanistic Insight to the Reaction Pathway. Angew. Chem. Int. Ed., 2012, 51, 12570-12574. (SCI一區(qū))
11. H. Liu, Z. Qiao and X. Jiang*. Palladium-Catalyzed Atom Transfer Radical Cyclization of Unactivated Alkyl Iodide. Org. Biomol. Chem., 2012, 10, 7274-7277.
10. X. Jiang*, H. Liu and Z. Gu. Carbon-Halogen Bond Formation by the Reductive Elimination of PdII Species. Asian J. Org. Chem., 2012, 1, 16-24.
9. K. Li, J. Hu, H. Liu and X. Tong*. Amine-catalyzed formal (3+3) annulations of 2-(acetoxymethyl)buta-2,3-dienoate with sulfur ylides: synthesis of 4H-pyrans bearing a vinyl sulfide group. Chem. Commun., 2012, 48, 2900-2902.
8. W. Li, H. Liu, X. Jiang*, J. Wang*. Enantioselective Organocatalytic Conjugate Addition of Nitroalkanes to Electrophilic 2-Iminochromenes. ACS Catal., 2012, 2, 1535-1538.
7. X. Jiang*, L. Shi, H. Liu, Akbar H. Khan and Jason S. Chen. Gas Extrusion in Natural Products Total Synthesis. Org. Biomol. Chem., 2012, 10, 8383-8392.
6. P. Wu, H. Liu, X. Tong*. Synthesis of 3-pyrroline via domino Heck-aza-Michael reaction. Tetrahedron Lett., 2012, 53, 4673-4675.
5. Q. Ren, J. Huang, L. Wang, W. Li, H. Liu, X. Jiang* and J. Wang*. Highly Efficient Assembly of 3 Hydroxy Oxindole Scaffold via a Catalytic Decarboxylative [1,2]-Addition Strategy. ACS Catalysis, 2012, 2, 2622-2625.
4. H. Liu, C. Li, D. Qiu* and X. Tong*. Palladium-Catalyzed Cycloisomerizations of (Z)-1-Iodo-1,6-dienes: Iodine Atom Transfer and Mechanistic Insight to Alkyl Iodide Reductive Elimination. J. Am. Chem. Soc., 2011, 133, 6187-6193.
3. H. Liu, C. Chen, L. Wang and X. Tong*. Pd(0)-Catalyzed Iodoalkynation of Norbornene Scaffolds: The Remarkable Solvent Effect on Reaction Pathway. Org. Lett., 2011, 13, 5072-5075.
2. H. Liu, L. Wang and X. Tong*. Palladium-Catalyzed Heck-type Reaction of Oxime Ether Bearing a Pendant Vinyl Iodide Moiety. Chem.Comm., 2011, 47, 12206-12208.
1. H. Liu, J. Yu, L. Wang, X. Tong*. Cyclization–oxidation of 1,6-enyne derivatived from Baylis–Hillman adducts via Pd(II)/Pd(IV)-catalyzed reactions: stereoselective synthesis of multi-substituted bicyclo[3.1.0] hexanes and insight into reaction pathways. Tetrahedron Lett., 2008, 49, 6924-6928.

【授權(quán)專利】
1. 姜雪峰，汪艦，劉會(huì)，李文軍，3,3-二取代-2-氧化吲哚類化合物的不對(duì)稱合成方法。
專利授權(quán)號(hào)：ZL 2012 1 0093045.9
2．姜雪峰，劉會(huì)，喬宗君，一種2,3-二氫-[1,4]-苯并噻嗪類化合物的合成方法。
專利授權(quán)號(hào)：ZL 2013 1 0028082.6
3. 劉會(huì)，劉青，董云會(huì)，李峻，胡義甜，朱玉花，一種多取代的α-乙酰氧基-α，β-烯酮類化合物的合成方法。
專利授權(quán)號(hào)：ZL 2016 1 0310198.2
4. 劉會(huì)，韓穎，董旭，劉青，董云會(huì)，許正帥，白占猛，曹風(fēng)亮，一種3-甲基-1-對(duì)甲苯磺�；�四氫吡咯類化合物的合成方法。
  專利授權(quán)號(hào)：ZL 2016 1 0455519.8
5. 劉會(huì)，閆法超，董旭，董云會(huì)，劉青，王平，梁寒冰，一種3-苯基-哌啶類衍生物合成方法。
   專利授權(quán)號(hào)：ZL 2016 1 0518448.1
6. 劉青，董云會(huì)，劉會(huì)，李峻，董旭，閆法超，一種5,10-二氫吲哚[3,2-b]吲哚類化合物的合成方法。
專利授權(quán)號(hào)：ZL 2015 1 0911887.4
7. 劉會(huì)，劉青，董云會(huì)，董旭，韓穎，許正帥，白占猛，曹風(fēng)亮，一種5-苯基-1,2,3,6-四氫吡啶衍生物的合成方法。
專利授權(quán)號(hào)：ZL 2016 1 0310197.8

【著作】
1. Hui Liu, X. Jiang*.
Application of Zinc catalysts in Total Synthesis in Zinc Catalysis-Applications in Organic Synthesis Ed. Stephan Enthaler and Xiao-Feng Wu, Wiley-VCH, 2014, 219-273.

2. X. Jiang*, Hui Liu
Electrophilic Cyclizations in Comprehensive Organic Synthesis 2nd Edition, Ed. Gary Molander and Paul Knochel, Oxford: Elsevier, 2014, Vol 4, 412-497.

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