>As indicated by the 3rd referee, the progression and therapeutic information is fine but how prognosis is studied is not clear without a follow-up data?（如何進(jìn)一步對(duì)預(yù)后進(jìn)行研究呢）
>
>No validation has been done for key regulatory genes in primary clinical samples.   This is essential.
>（關(guān)鍵調(diào)控基因需要在最初的臨床樣品中驗(yàn)證，但是純生信的我怎么回答呢。。。）

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