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[資源]
Chitosan-based Systems for Biopharmaceuticals
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Chitosan-based Systems for Biopharmaceuticals: Delivery, Targeting and Polymer Therapeutics Bruno Sarmento, Jose das Neves Wiley 2012 ISBN: 0470978325 Chitosan is a linear polysaccharide commercially produced by thedeacetylation of chitin. It is non–toxic, biodegradable,biocompatible, and acts as a bioadhesive with otherwise unstablebiomolecules – making it a valuable component in the formulation ofbiopharmaceutical drugs. Chitosan–Based Systems for Biopharmaceuticals provides anextensive overview of the application of chitosan and itsderivatives in the development and optimisation ofbiopharmaceuticals. The book is divided in four different parts.Part I discusses general aspects of chitosan and its derivatives,with particular emphasis on issues related to the development ofbiopharmaceutical chitosan–based systems. Part II deals with theuse of chitosan and derivatives in the formulation and delivery ofbiopharmaceuticals, and focuses on the synergistic effects betweenchitosan and this particular subset of pharmaceuticals. Part IIIdiscusses specific applications of chitosan and its derivatives forbiopharmaceutical use. Finally, Part IV presents diverse viewpointson different issues such as regulatory, manufacturing andtoxicological requirements of chitosan and its derivatives relatedto the development of biopharmaceutical products, as well as theirpatent status, and clinical application and potential. Chitosan–Based Systems for Biopharmaceuticals is animportant compendium of fundamental concepts, practical tools andapplications of chitosan–based biopharmaceuticals for researchersin academia and industry working in drug formulation and delivery,biopharmaceuticals, medicinal chemistry, pharmacy, bioengineeringand new materials development. 00336d80.jpg |
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