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jdy1947

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[求助] 求翻譯一段摘要

Thiazole is a valuable scaffold in the field of medicinal chemistry and has accounted to display a variety of
biological activities. Thiazole and its derivatives have attracted continuing interest to design various
novel CNS active agents. In the past few decades, thiazoles have been widely used to develop a variety of
therapeutic agents against numerous CNS targets. Thiazole containing drug molecules are currently
being used in treatment of various CNS disorders and a number of thiazole derivatives are also presently
in clinical trials. A lot of research has been carried out on thiazole and their analogues, which has proved
their efficacy to overcome several CNS disorders in rodent as well as primate models. The aim of present
review is to highlights diverse CNS activities displayed by thiazole and their derivatives. SAR of this
nucleus has also been well discussed. This review covers the recent updates present in literature and will
surely provide a greater insight for the designing and development of potent thiazole based CNS active
agents in future.

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jdy1947: 金幣+50, 翻譯EPI+1, ★★★★★最佳答案 2016-05-03 08:12:31

Thiazole is a valuable scaffold in the field of medicinal chemistry and has accounted to display a variety of biological activities. Thiazole and its derivatives have attracted continuing interest to design various novel CNS active agents.
作為醫(yī)療化學(xué)領(lǐng)域的一種重要的支架，噻唑能作用于各種生物活動(dòng)中。人們一直在嘗試基于噻唑和其衍生物設(shè)計(jì)各種新型活性劑。

In the past few decades, thiazoles have been widely used to develop a variety of therapeutic agents against numerous CNS targets. Thiazole containing drug molecules are currently being used in treatment of various CNS disorders and a number of thiazole derivatives are also presently in clinical trials.
在過去的幾十年里，噻唑被廣泛運(yùn)用于開發(fā)各種的治療劑，以治療治療中樞神經(jīng)系統(tǒng)疾病�，F(xiàn)在，含有藥物分子的噻唑用于治療各種中樞神經(jīng)系統(tǒng)失調(diào)疾病，同時(shí)大量的噻唑衍生物目前也用于臨床試驗(yàn)。

A lot of research has been carried out on thiazole and their analogues, which has proved their efficacy to overcome several CNS disorders in rodent as well as primate models. The aim of present review is to highlights diverse CNS activities displayed by thiazole and their derivatives. SAR of this nucleus has also been well discussed.
人們已經(jīng)進(jìn)行了大量研究來研究噻唑及其類似物，這些研究已證明了噻唑在客服嚙齒動(dòng)物和靈長類動(dòng)物各種中樞神經(jīng)系統(tǒng)失調(diào)疾病的效率。本綜述的目的是凸顯噻唑及其衍生物在各種中樞神經(jīng)系統(tǒng)中的活動(dòng)。核心的SAR也已經(jīng)很好的討論過了

This review covers the recent updates present in literature and will surely provide a greater insight for the designing and development of potent thiazole based CNS active agents in future.
本綜述包含了最近文獻(xiàn)更新，毫無疑問為未來基于中樞神經(jīng)系統(tǒng)活性劑研發(fā)有效噻唑提供一種更新的視角。

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