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小木蟲論壇-學術科研互動平臺 » 學術交流區(qū) » 論文投稿 » 其他 » 跪求檢索號
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| 跪求Silymarin versus Silibinin: Differential Antioxidant and Neuroprotective Effects against H2O2-induced Oxidative Stress in PC12 Cells.這篇文章的檢索號！ |
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muchong_li
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2樓2016-10-28 11:00:11
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609718476: 金幣+12, ★★★★★最佳答案 2016-10-28 11:30:28
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609718476: 金幣+12, ★★★★★最佳答案 2016-10-28 11:30:28
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Silymarin versus Silibinin: Differential Antioxidant and Neuroprotective Effects against H2O2-induced Oxidative Stress in PC12 Cells 作者:Jiang, HH (Jiang, Hui-Hui)[ 1 ] ; Yan, FS (Yan, Fa-Shun)[ 1 ] ; Shen, L (Shen, Liang)[ 1 ] ; Ji, HF (Ji, Hong-Fang)[ 1 ] NATURAL PRODUCT COMMUNICATIONS 卷: 11 期: 5 頁: 633-636 出版年: MAY 2016 查看期刊信息 摘要 The present study assessed comparatively the antioxidant activities of silymarin and its major active component silibinin and their neuroprotective effects against hydrogen peroxide (H2O2)-induced oxidative stress in rat pheochromocytoma PC12 cells. It was found that despite newly prepared silymarin and silibinin solution possessing comparable superoxide anion (O-2(center dot-))-scavenging activities, with time the activity of silymarin lowered slightly, but that of silibinin decreased dramatically. Both silymarin and silibinin suppressed H2O2 -induced oxidative stress and apoptosis, and the neuroprotective effect of silymarin was overall relatively stronger than that of silibinin. The findings provided clues for future studies on therapeutic potentials of the whole silymarin or purified silibinin for neurodegenerative diseases. 關鍵詞 作者關鍵詞:Silymarin; Silibinin; Neurodegenerative diseases; Neuroprotective effects; PC12 cells KeyWords Plus:THISTLE SILYBUM-MARIANUM; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; MILK THISTLE; NEURODEGENERATIVE DISEASES; MECHANISMS; MODEL; PREVALENCE; DISORDERS; APOPTOSIS 作者信息 通訊作者地址: Shen, L; Ji, HF (通訊作者) 顯示增強組織信息的名稱 Shandong Univ Technol, Sch Life Sci, Shandong Prov Res Ctr Bioinformat Engn & Tech, Zibo 255049, Peoples R China. 地址: 顯示增強組織信息的名稱 [ 1 ] Shandong Univ Technol, Sch Life Sci, Shandong Prov Res Ctr Bioinformat Engn & Tech, Zibo 255049, Peoples R China 電子郵件地址:shen@sdut.edu.cn; jhf@sdut.edu.cn 基金資助致謝 基金資助機構(gòu) 授權號 Shandong Provincial Science Foundation for Distinguished Young Scholars JQ201508 Shandong Provincial Science Foundation ZR2015JL010 ZR2014CL008 查看基金資助信息 出版商 NATURAL PRODUCTS INC, 7963 ANDERSON PARK LN, WESTERVILLE, OH 43081 USA 類別 / 分類 研究方向  harmacology & Pharmacy; Food Science & TechnologyWeb of Science 類別:Chemistry, Medicinal; Food Science & Technology 文獻信息 文獻類型:Article 語種:English 入藏號: WOS:000375633500020 PubMed ID: 27319137 ISSN: 1934-578X eISSN: 1555-9475 期刊信息 目錄： Current Contents Connect® Impact Factor (影響因子): Journal Citation Reports® 其他信息 IDS 號: DL4UO Web of Science 核心合集中的 "引用的參考文獻": 32 Web of Science 核心合集中的 "被引頻次": 0 |
3樓2016-10-28 11:14:58
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4樓2016-10-28 11:18:00
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