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2808704855木蟲 (正式寫手)
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[求助]
Biomedicine & Pharmacotherapy審稿意見是啥意思 已有1人參與
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最近 Biomedicine & Pharmacotherapy的審稿意見回來了，不確定是審稿人具體的意思，想向各位大神求助一下，具體的審稿意見如下： -Reviewer 1 Dear Authors The study investigated the effect of xanthones from Gentianella acuta on I/R injury and tried to illuminate the mechanism of its cardiaprotective effect. I think the intensive study is well organized. The results are very promising. However, the manuscript could have been written better. it need english editing in minor extent. for examples; The first paragraph of the discussion is not convenient for discussion, it must be in the introduction section. page 17, line 3 "we investigated the effects of xanthones on cardiac function" this sentence is not convenient for discussion. page 4, line 8: "improve" can be "improved" page 10, line 8: instead of "this found", this finding is more appropriate. page 18, line 4, "the enzymes in intracellular" must be "the intracellular enzymes The color of Fig 2 is not distinctive if it is not color printing 這位審稿人的意思是讓我小修一下，只要把如下幾個錯誤改一下，還是他只是舉了幾個例子，其他的讓我好好看看，改正此類錯誤。 Reviewer 2 this manuscript the authors describes the beneficial effects of xanthones from G.acuta against myocardial I/R injury in isolated rat hearts using Langendoff system. The data provided in the study largely demonstrates and supports the hypothesis proposed by the authors. However I have the following comments that can strengthen the manuscript. 1) Even though there are many parameters such as LDH assay, Bcl/Bax ratio indicate that G.acuta can prevent cellular apoptosis, there is a lack of mechanistic explanations to this observation. What is the signaling cascade involved in the effect of G.Acuta. Whether Bcl2/Bax is regulated via AKT, AMPK, ERK or is it a direct effect of G.acuta on mitochondria is not clear. 這位審稿人的意思是讓我按他提的意見補(bǔ)一下實驗，還是讓我按他的意見好好改一下文中表達(dá)的意思。 雜志社一共給我60天的修改時間，是不是打算讓我補(bǔ)實驗啊? |
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paperhunter
榮譽(yù)版主 (文學(xué)泰斗)
還沒想好
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2樓2017-05-04 23:52:32
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這個簡單呀。第一個審稿人的意見你按照他說的一改就好了。第二個審稿人的意思，我猜想你是做了蛋白表達(dá)的。他的意思是，你的東西缺少機(jī)理，讓你確定具體的機(jī)制，你就按照他給你提的那幾個，你可以選擇一條通路補(bǔ)一下相關(guān)蛋白表達(dá)。因為你要補(bǔ)實驗，所以給你兩個月時間，很正常。好好修改，加油。我的也在修改，好艱難，一起加油吧 發(fā)自小木蟲Android客戶端 |
3樓2017-05-05 00:05:56
小葉子2015
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4樓2018-01-01 21:56:54
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