 |
 |
 |
 |
 |
 |
||
 |
 |
 |
 |
 |
| 查看: 1740 | 回復: 14 | |||
Strawberrix新蟲 (小有名氣)
|
[交流]
荷蘭讀博CSC全獎，系統(tǒng)生物學項目 (Maastricht University)
|
|
項目：Modeling the Metabolic Diversity of the Brain’s Glial Cells Maastricht和csc的項目。感興趣者請將英文版cv和transcript發(fā)送至 prof. dr. renaud jolivet (r.jolivet@maastrichtuniversity.nl) 以及 dr. marian breuer （marian.breuer@maastrichtuniversity.nl） 并向他們直接咨詢其他信息。 project title: modeling the metabolic diversity of the brain’s glial cells project leader: prof. dr. renaud jolivet, dr. marian breuer function: professor of neural engineering and computation collaborators: prof. dr. ilja arts proposal (250 words): introduction: the brain consists of a variety of cell types, and neurons only constitute around half of the brain cell population. the other cell populations, collectively known as glial cells, support and interact with neurons in various ways. glial cells play a pivotal role in normal brain function as well as neurodegenerative and other disorders, and thus their understanding is of importance in the context of public health. however, while glial cells are known to play an important role in brain metabolism overall, their particular metabolic functions and interactions are far from understood. hypothesis and objectives: this project will study the metabolic functions of different types of glial cells, as well as their metabolic interactions, and how these are affected in aging and different pathological conditions. setting and methods: the project will make use of large publicly available neuroscience transcriptome data sets to build models of the metabolic network of various types of glial cells, and to study how these glial cells interact with each other in the brain. the project will then make use of other transcriptomes to investigate these interactions in aging and in various diseases of the central nervous system. impact: the metabolic functions and interactions of glial cells in normal brain function address an important knowledge gap in basic neuroscience; while their perturbations in aging, neurodegenerative diseases and other pathological conditions could help to elucidate disease mechanisms as well as suggest potential intervention strategies ╟ with strong potential impact in healthy aging and disease diagnosis and therapy. requirements candidate: highly motivated student with good english communication skills and proactive and resolute attitude. the project requires good programming skills and an interest for the complexity and diversity of the brain’s heterocellular population. the ideal candidate would have a foundation in biochemistry and cellular metabolism on the one hand, and some computational skills on the other hand, preferably in matlab. applications with background in only the biochemical or computational side are still welcome, if the applicant can make a case for being able to catch up in the other aspect. keywords: biological foundations of human health and diseases, computational biology, systems biology, metabolic modeling, neuroscience, aging top 5 selected publications: 1. cullen cl, pepper re, clutterbuck mt, pitman ka, oorschot v, auderset l, tang ad, ramm g, emery b, rodger j, jolivet rb & young km “periaxonal and nodal plasticities modulate action potential conduction in the adult mouse brain” cell rep. (2021), 34:108641. citations (web of science): 29 2. caruso g, caraci f & jolivet rb “pivotal role of carnosine in the modulation of brain cells activity: multimodal mechanism of action and therapeutic potential in neurodegenerative disorders” progress in neurobiol. (2019), 175:35. citations (web of science): 62 3. madry c*, kyrargyri v*, arancibia-cárcamo il*, jolivet rb*, kohsaka s, bryan rm & attwell d “microglial ramification, surveillance, and interleukin-1β release are regulated by the two-pore domain k+ channel thik-1” neuron (2018), 97:299. citations (web of science): 232, top 1% cited in neuroscience & behaviour 4. m. breuer, t. m. earnest, c. merryman, k. s. wise, l. sun, m. r. lynott, c. a. hutchison iii, h. o. smith, j. d. lapek jr., d. j. gonzalez, v. de crécy-lagard, d. haas, a. d. hanson, p. labhsetwar, j. i. glass, z. luthey-schulten “essential metabolism for a minimal cell” elife (2019), 8:e36842. citations (web of science): 75 5. d. haas, a. m. thamm, j. sun, l. huang, l. sun, g. a. w. beaudoin, k. s. wise, c. lerma-ortiz, s. d. bruner, m. breuer, z. luthey-schulten, j. lin, m. a. wilson, g. brown, a. f. yakunin, i. kurilyak, j. folz, o. fiehn, j. i. glass, a. d. hanson, c. s. henry, v. de crécy-lagard. “metabolite damage and damage control in a minimal genome” mbio (2022), 13:e01630-22. citations (web of science): 5 additional details: - duration: four years - no mandatory course work - english: good score on toefl, ielts or other test beneficial, but english language skills will be gauged primarily during personal interview - cooperative program - maastricht university has limited number of reserved spots; beyond these, application through general program possible - further information: - www.maastrichtuniversity.nl/um-china-team#um-csc - www.maastrichtuniversity.nl/phd-project-outlines - contact details: - dr. marian breuer: marian.breuer@maastrichtuniversity.nl - prof. dr. renaud jolivet: r.jolivet@maastrichtuniversity.nl |
回復此樓» 猜你喜歡
材料調(diào)劑
已經(jīng)有5人回復
-
081700 調(diào)劑 267分
已經(jīng)有8人回復
-
請教下大家 2026年國家基金申請是雙盲審嗎？
已經(jīng)有5人回復
-
276求調(diào)劑。有半年電池和半年高分子實習經(jīng)歷
已經(jīng)有10人回復
-
一志愿南航材料專317分求調(diào)劑
已經(jīng)有4人回復
-
求調(diào)劑
已經(jīng)有4人回復
-
生物學學碩求調(diào)劑
已經(jīng)有5人回復
-
284求調(diào)劑
已經(jīng)有10人回復
-
一志愿山東大學藥學學碩求調(diào)劑
已經(jīng)有4人回復
-
07化學280分求調(diào)劑
已經(jīng)有4人回復
Strawberrix
新蟲 (小有名氣)
| 頂 |
2樓2023-10-18 13:28:00
Strawberrix
新蟲 (小有名氣)
- 應助: 0 (幼兒園)
- 金幣: 700.8
- 散金: 53
- 帖子: 153
- 在線: 19.6小時
- 蟲號: 3260471
- 注冊: 2014-06-07
- 專業(yè): 細胞生物學研究中的新方法
3樓2023-10-19 21:47:27
Strawberrix
新蟲 (小有名氣)
- 應助: 0 (幼兒園)
- 金幣: 700.8
- 散金: 53
- 帖子: 153
- 在線: 19.6小時
- 蟲號: 3260471
- 注冊: 2014-06-07
- 專業(yè): 細胞生物學研究中的新方法
4樓2023-10-24 10:20:03
Strawberrix
新蟲 (小有名氣)
| Up |
5樓2023-11-09 09:50:21
Strawberrix
新蟲 (小有名氣)
| Up |
6樓2023-11-12 21:04:16
Strawberrix
新蟲 (小有名氣)
| up |
7樓2023-11-14 20:11:37
Strawberrix
新蟲 (小有名氣)
| up |
8樓2023-11-20 10:00:31
Strawberrix
新蟲 (小有名氣)
| up |
9樓2023-12-04 11:04:43
這兩位老板咋樣？我看您主頁這兩年都有該課題組csc項目招生，是一直沒招到人嗎？碩士做astrocyte的時候會有機會嗎？招生導師好像做computional biology，沒有相關基礎啊 發(fā)自小木蟲Android客戶端 |
10樓2023-12-09 00:06:40
相關版塊跳轉(zhuǎn)
我要訂閱樓主 Strawberrix 的主題更新
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 求調(diào)劑 +7 | 十三加油 2026-03-21 | 7/350 |
|
|---|---|---|---|---|
|
|
[考研] 工科0856求調(diào)劑 +5 | 沐析汀汀 2026-03-21 | 5/250 |
|
|
|
[考研] 求老師收我 +3 | zzh16938784 2026-03-23 | 3/150 |
|
|
[考研]
 一志愿東華大學化學070300，求調(diào)劑
+7
|
2117205181 2026-03-21 | 8/400 |
|
|
|
[考研] 求調(diào)劑院校信息 +6 | CX 330 2026-03-21 | 6/300 |
|
|
|
[考研] 材料與化工（0856）304求B區(qū)調(diào)劑 +3 | 邱gl 2026-03-20 | 7/350 |
|
|
|
[考研] 297求調(diào)劑 +11 | 戲精丹丹丹 2026-03-17 | 12/600 |
|
|
|
[考研] 296求調(diào)劑 +4 | www_q 2026-03-20 | 4/200 |
|
|
|
[考研] 0805材料320求調(diào)劑 +3 | 深海物語 2026-03-20 | 3/150 |
|
|
|
[考研] 一志愿天津大學化學工藝專業(yè)（081702）315分求調(diào)劑 +12 | yangfz 2026-03-17 | 12/600 |
|
|
|
[考研] 324分 085600材料化工求調(diào)劑 +4 | llllkkkhh 2026-03-18 | 4/200 |
|
|
|
[考研] 一志愿武理材料305分求調(diào)劑 +6 | 想上岸的鯉魚 2026-03-18 | 7/350 |
|
|
|
[考研] 材料學求調(diào)劑 +4 | Stella_Yao 2026-03-20 | 4/200 |
|
|
|
[考研] 261求B區(qū)調(diào)劑，科研經(jīng)歷豐富 +3 | 牛奶很忙 2026-03-20 | 4/200 |
|
|
|
[考研] 一志愿南理工085701環(huán)境302求調(diào)劑院校 +3 | 葵梓衛(wèi)隊 2026-03-20 | 3/150 |
|
|
|
[考研] 086500 325 求調(diào)劑 +3 | 領帶小熊 2026-03-19 | 3/150 |
|
|
|
[考研] 廣西大學家禽遺傳育種課題組2026年碩士招生（接收計算機專業(yè)調(diào)劑） +3 | 123阿標 2026-03-17 | 3/150 |
|
|
|
[考研] 085410人工智能專碩317求調(diào)劑（0854都可以） +4 | xbxudjdn 2026-03-18 | 4/200 |
|
|
|
[論文投稿]
申請回稿延期一個月，編輯同意了。但系統(tǒng)上的時間沒變，給編輯又寫郵件了，沒回復
 10+3
|
wangf9518 2026-03-17 | 4/200 |
|
|
|
[考研] 考研求調(diào)劑 +3 | 橘頌. 2026-03-17 | 4/200 |
|