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wangqk198738金蟲 (正式寫手)
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Kozak consensus 已有1人參與
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我曾經(jīng)為了這個(gè)定義頭疼,偶然在網(wǎng)上找到了英文的原版和中文的簡(jiǎn)介,給大家分享一下。 The Kozak consensus sequence is gccgcc(A/G)ccAUGG, and is the sequence on an mRNA molecule recognized by the ribosome as the translational start site, from which point a protein is coded by that mRNA molecule. The ribosome requires this sequence, or a possible variation (see below) to initiate translation, or the production of protein. The Kozak sequence is not to be confused with the ribosomal binding site, that being either the 5′ cap of a messenger RNA, or mRNA, or an Internal Ribosome Entry Sequence, or IRES] 在真核生物中起始密碼子幾乎都是5—AUG—3,它包含在一段短的通用序列5—ACCAUGG—3,因而可以被識(shí)別,這段序列就是Kozak sequence ?纯聪旅娴倪@個(gè)網(wǎng)頁(yè)也可以。 http://202.165.105.226/babelfish ... _consensus_sequence [ Last edited by wangqk198738 on 2009-11-8 at 15:41 ] |
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