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ww6319499金蟲(chóng) (小有名氣)
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求助�。�！藥劑學(xué)畢業(yè)論文翻譯.急急急�。�！
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對(duì)有些專業(yè)詞匯把握不準(zhǔn)，不敢用網(wǎng)絡(luò)翻譯。求幫忙�。。。∫韵率乔笾鷥�(nèi)容 本實(shí)驗(yàn)以小檗堿為模型藥物，以乳化干燥法制備脂質(zhì)體。以大豆磷脂為表面活性劑，聚乙二醇為支架劑，溶于有機(jī)相，小檗堿、0%（2.5%，5%，10%）蔗糖（凍干保護(hù)劑）溶于水相，按油相/水相為3：1的體積比例混合，超聲乳化，得W/O型乳劑。將乳劑凍干，得到凍干品，再水化形成脂質(zhì)體。本實(shí)驗(yàn)采用單因素設(shè)計(jì)，考察適宜的溶劑、磷脂用量和附加劑,以包封率為指標(biāo)對(duì)此方法進(jìn)行驗(yàn)證。用這種方法得到的凍干品包封率高，性質(zhì)穩(wěn)定，可長(zhǎng)期保存。 關(guān)鍵詞：脂質(zhì)體 制備 W/O型乳劑 乳化凍干法 包封率 |
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jingjing1005
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ww6319499
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jingjing1005
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ww6319499(金幣+10, 翻譯EPI+1): 2010-06-09 10:29:51
zehuac(金幣+1, 翻譯EPI+1):謝謝參與哈，希望以后更加積極的應(yīng)助 2010-06-16 15:19:44
ww6319499(金幣+10, 翻譯EPI+1): 2010-06-09 10:29:51
zehuac(金幣+1, 翻譯EPI+1):謝謝參與哈，希望以后更加積極的應(yīng)助 2010-06-16 15:19:44
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In this research, liposomes were prepared by emulsion drying method with berberine as model drug. The organic phase, with soy lecithin as surfactant, polyethylene glycol as scaffold, together with the water phase dissolving berberine, 0% (2.5%, 5%, 10%) and sucrose (preservative) were mixed according to oil phase / water phase volume ratio of 3:1. W / O type emulsions were obtained after ultrasonic emulsification, and then freeze-dried products were gained after lyophilization, finally the liposomes formatted by rehydrating. In this study, a single factor experiment was designed to detect the appropriate solvent, phospholipid content and additive, furthermore the chosen experiment method was validated by the index of encapsulation efficiency. Therefore, the freeze-dried products obtained in this way are of high encapsulation efficiency, stable properties and long-term preservation. Keywords: Liposome, W / O type emulsion, emulsion lyophilization , encapsulation efficiency |
4樓2010-06-09 10:11:44
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