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Informative diagnostics for personalized medicine
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Sample TextSample TextSample Text Upstream of an in vitro diagnostic platform, there are outstanding opportunities for chemical biologists to both identify and create affinity recognition strategies for disease biomarkers, which may be discovered at the genomic, transcriptomic, proteomic or metabolomic levels. In the clinic, informative biomarkers may be used in many ways13, including as preclinical diagnostic biomarkers for presymptomatic detection, prognostic biomarkers, which forecast disease progression, and theragnostic biomarkers, which suggest the most appropriate treatment strategy, such as Her2 in the case of trastuzumab. |
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可為個性化醫(yī)學(xué)提供相關(guān)信息的診斷 在生物體診斷平臺的上游,在染色體組、翻錄本以及新陳代謝水平上,生物化學(xué)家有很好的機(jī)會來證實與用于疾病的生物標(biāo)記的類同性識別策略。在治療過程中,生物標(biāo)記物可提供相關(guān)信息并有很多利用方式,包括作為前期治療、診斷性的生物標(biāo)記物可用于前期癥狀的檢測,預(yù)兆性的生物標(biāo)記可以預(yù)測疾病的發(fā)展,theragnostic 生物標(biāo)記可對治療提供最合適策性略建議,如Her2用于曲妥珠單抗中。 |
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