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求助如何查到往年中標(biāo)的基金申請(qǐng)書摘要
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| 本人第一次寫青年基金,身邊沒有人撰寫,想?yún)⒖家幌聞e人的版本,在國(guó)基網(wǎng)上只能查到項(xiàng)目名稱和編號(hào),哪位高人賜教:到哪可以查到已中項(xiàng)目的摘要?謝謝 |
» 搶金幣啦!回帖就可以得到:
+1/92
+1/82
+1/80
+1/47
+2/40
+2/36
+1/34
+1/26
+1/25
+1/14
+1/14
+1/11
+1/7
+1/7
+1/7
+1/5
+1/5
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+1/4
+1/3
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剛試用過(guò),例如: 名稱:共表達(dá)RSV中和抗原的DNA和非復(fù)制型腺病毒重組體的構(gòu)建及其保護(hù)作用 ------------------------------------------------------- 中文摘要: RSV是導(dǎo)致嬰幼兒嚴(yán)重下呼吸道感染的最重要的病毒病原,同時(shí)也是引起老人發(fā)病和死亡的重要原因。病毒感染機(jī)體后的免疫保護(hù)機(jī)制尚未明確,也無(wú)特異性防治方法。以真核表達(dá)質(zhì)粒和非復(fù)制型腺病毒為載體共表達(dá)RSV兩種中和抗原F和G,并研究其免疫保護(hù)作用是探索RSV疫苗的有益嘗試。目前,已經(jīng)完成研究計(jì)劃中的一些重要內(nèi)容,如兩種RSV中和抗原編碼基因的克隆,重組腺病毒簡(jiǎn)便高效的改建方法,可進(jìn)行共表達(dá)的腺病毒載體系統(tǒng)的構(gòu)建,分別表達(dá)F和G蛋白的非復(fù)制型腺病毒重組體的構(gòu)建和鑒定工作等。已培養(yǎng)碩士研究生3名,發(fā)表論文4篇,其中核心期刊3篇。這些工作為繼續(xù)完成余下的課題任務(wù)奠定了基礎(chǔ)。 中文主題詞: 呼吸道合胞病毒;腺病毒重組體;免疫保護(hù)作用;中和抗原;共表達(dá) 英文摘要: Human respiratory syncytial virus (RSV) is the most important viral etiologic agent of pediatric lower respiratory tract disease worldwide. RSV disease is also responsible for considerable morbidity and mortality in the elderly. The mechanisms that contribute to the disease protection are not fully understood. Currently no safe and efficacious RSV vaccine is available. It will be helpful for the RSV vaccine program to investigate their expression and protective immunity of DNA and replication-defective adenoviral recombinants encoding the attachment (G) and fusion (F) protein. Till now, we have finished the clone and eukaryotic expression of F and G gene of subgroup A Long strain RSV, established a more effective and easier method for constructing recombinant adenovirus based on AdEasy System, constructed replication deficient adenovirus vector system used as expressing F and G protein simultaneously and the adenoviral recombinants expressing the F and G protein, respectively. All these achievements provide a good basis for further study. 英文主題詞: respiratory syncytial virus;protective immunity;adenovirus recombinant;neutralization antigen;co-expression |
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http://npd.nsfc.gov.cn/ResearchNet_NSFC/index.aspx 點(diǎn)擊-->生命科學(xué)部, 點(diǎn)擊-->資助項(xiàng)目, 點(diǎn)擊-->標(biāo)題, 最后點(diǎn)擊-->項(xiàng)目摘要。 |
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