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北京石油化工學(xué)院2026年研究生招生接收調(diào)劑公告

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煙云聽雨

鐵桿木蟲 (正式寫手)

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[求助] 求翻譯一段英文（藥化）

The extracts of stemonaceous flora have been utilized for centuries as treatments for respiratory ailments in established Asian traditions. Additional effects associated with these plants (or discrete compounds isolated from them) include insecticidal,
anthelmintic, antitussive, and various neurochemical actions (11–17), although the molecular mechanisms responsible for their activities have rarely been identified (18). Four structurally related isolated Stemona alkaloid molecules are depicted in
Fig. 1. The reported antitussive activities of two isolated Stemona alkaloid compounds, neostenine 3 and neotuberostemonine 4 against citric acid-induced cough in guinea pig animal models have validated the traditional medicine uses for these plants (19, 20). More recently, antitussive activity has been confirmed for additional isolated Stemona alkaloid compounds (21–23).The diversity of reported traditional uses combined with demonstrated in vivo activity of several members supported the pursuit of an appropriately simplified Stemona alkaloid structure for
speculative screening.

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1樓 2011-06-06 11:14:49

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chzhbin

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★ ★
ringzhu(金幣+1): 多謝交流歡迎常來端午快樂~~ 2011-06-06 15:36:40
sltmac(金幣+1): 謝謝交流~~ 2011-06-06 18:18:48
煙云聽雨(金幣+15, 翻譯EPI+1): 謝謝 2011-06-06 18:46:09

在亞洲人的傳統(tǒng)中，stemonaceous 群提取物被用來治療呼吸系統(tǒng)疾病有幾個(gè)世紀(jì)之久，盡管活性的分子機(jī)制還沒有得到證實(shí)，那些植物（分離出的化合物）還有殺蟲、驅(qū)蟲、止咳及許多影響神經(jīng)系統(tǒng)的作用。圖1中為分離出的四個(gè)結(jié)構(gòu)相關(guān)的百部生物堿結(jié)構(gòu)。neostenine 3和neotuberostemonine 4 對(duì)于檸檬酸所致的豚鼠咳嗽的止咳作用證實(shí)了這些植物的傳統(tǒng)藥用。最近，分離出的百部生物堿化合物21-23的止咳活性得到證實(shí)，傳統(tǒng)應(yīng)用的多樣性以及已經(jīng)證實(shí)的幾個(gè)化合物的體內(nèi)活性支持百部生物堿的結(jié)構(gòu)適當(dāng)簡(jiǎn)化以用來篩選!

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2樓2011-06-06 13:55:24