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煙云聽雨鐵桿木蟲 (正式寫手)
金蟲
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[求助]
求助有機化學(xué)翻譯一小段
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We therefore did not feel constrained in the range of chemical manipulations we could explore, and in many cases the final compounds bear little resemblance to any known Stemona alkaloid. Herein, we report the initial evaluation of these compounds against a panel of G protein-coupled receptor (GPCR) targets relevant to central nervous system function and how those results have inspired additional library design, ultimately resulting in a series of highly potent Sig-R ligands. |
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8814402
至尊木蟲 (職業(yè)作家)
- 翻譯EPI: 509
- 應(yīng)助: 18 (小學(xué)生)
- 貴賓: 0.381
- 金幣: 12916.1
- 散金: 47
- 紅花: 16
- 帖子: 4183
- 在線: 357.8小時
- 蟲號: 1184404
- 注冊: 2011-01-06
- 專業(yè): 藥物學(xué)其他科學(xué)問題
【答案】應(yīng)助回帖
煙云聽雨(金幣+5, 翻譯EPI+1): 謝謝！ 2011-07-13 12:36:40
| We therefore did not feel constrained in the range of chemical manipulations we could explore, and in many cases the final compounds bear little resemblance to any known Stemona alkaloid. 因而我們廣泛的探索了多種化學(xué)手段，在許多情況下，最終得到的化合物與任何已知的百部生物堿幾乎沒有相似之處。Herein, we report the initial evaluation of these compounds against a panel of G protein-coupled receptor (GPCR) targets relevant to central nervous system function and how those results have inspired additional library design, ultimately resulting in a series of highly potent Sig-R ligands.在此，我們報道這些化合物針對一組與中樞神經(jīng)系統(tǒng)功能相關(guān)的G蛋白偶聯(lián)受體靶標的初始評估，以及如何以這些結(jié)果指導(dǎo)更多的文庫設(shè)計來發(fā)現(xiàn)一系列的高效Sig-R配體。 |
2樓2011-07-13 10:32:38
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