| 2 | 1/1 | 返回列表 |
| 查看: 9532 | 回復(fù): 1 | |||
makuna木蟲 (正式寫手)
|
[交流]
fz-juelich.de 德國博士機會,請自行聯(lián)系 已有1人參與
|
|
Fachgebiete: Chemie Physik Thema: Doktorarbeit / Diplomarbeit: Studying interactions of Membrane Proteins with ligands Ansprechpartner: Prof. Henrike Heise Antwort an: h.heise@fz-juelich.de Institution: Physical Biology Ort: 52428 Jülich, ICS-6 ---------------------------------------------------------------------- Transmembrane receptors and their interaction with ligand molecules still impose a major challenge upon structural biology: In the membrane-reconstituted state, such proteins are not accessible with liquid-state NMR spectroscopy, and crystallization protocols are far from standard. In the past decade, solid-state NMR spectroscopy has developed into a promising tool for structure elucidation or even determination of immobilized proteins which do not have to be crystalline nor soluble. One of the largest obstackles in solid-state NMR spectroscopy is still the low sensitivity. However, the inherently low sensitivity of nuclear magnetization can be overcome by exploiting the 660 times higher magnetic moment of unpaired electrons for signal enhancement via dynamic nuclear polarization (DNP). In 2012 our group will be equipped with one of the first DNP-spectrometers operating at a proton frequency of 600 MHz, in addition to existing state-of-the art solid-state NMR spectrometers ra nging from 600 MHz to 800 MHz. We are investigating several membrane receptors and their interactions with ligands. We also develop techniques tailored to specific questions and signal enhancement, and especially DNP will provide ample opportunities for methods developments. The ideal candidate should have a strong background in Physics and Biochemistry. Basic knowledge and experience in NMR or EPR spectroscopy is an advantage. A strong interest in Physics and structural biology and is a prerequisite. The applicant should be highly motivated, open for new approaches and techniques, and able to tackle demanding challenges. Workplace will be the exquisitely equipped Forschungszentrum Juelich. Methoden: Festkörper-NMR-Spektroskopie Anfangsdatum: 9. Februar 2012 geschätzte Dauer: 3 Jahre Bezahlung: Forschungsschul-Stipendium Homepage: http://www.uni-duesseldorf.de/MathNat/fknmr/ |

新蟲 (初入文壇)
| 2 | 1/1 | 返回列表 |
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 生物學(xué)調(diào)劑 +5 | Surekei 2026-03-21 | 5/250 |
|
|---|---|---|---|---|
|
[考研] 285求調(diào)劑 +6 | ytter 2026-03-22 | 6/300 |
|
|
[考研] 生物學(xué)一志愿985,分數(shù)349求調(diào)劑 +4 | zxts12 2026-03-21 | 7/350 |
|
|
[考研] 化學(xué)工程321分求調(diào)劑 +18 | 大米飯! 2026-03-15 | 22/1100 |
|
|
[考研] 材料學(xué)碩333求調(diào)劑 +3 | 北道巷 2026-03-18 | 3/150 |
|
|
[考研] 297求調(diào)劑 +11 | 戲精丹丹丹 2026-03-17 | 12/600 |
|
|
[考研] 317求調(diào)劑 +9 | 申子申申 2026-03-19 | 15/750 |
|
|
[考研] 307求調(diào)劑 +3 | 余意卿 2026-03-18 | 3/150 |
|
|
[考研] 299求調(diào)劑 +6 | △小透明* 2026-03-17 | 6/300 |
|
|
[考研] 二本跨考鄭大材料306英一數(shù)二 +3 | z1z2z3879 2026-03-17 | 3/150 |
|
|
[考研] 296求調(diào)劑 +6 | www_q 2026-03-18 | 10/500 |
|
|
[考研] 考研調(diào)劑求學(xué)校推薦 +3 | 伯樂29 2026-03-18 | 5/250 |
|
|
[考研] 287求調(diào)劑 +7 | 晨昏線與星海 2026-03-19 | 8/400 |
|
|
[考研] 藥學(xué)383 求調(diào)劑 +3 | 藥學(xué)chy 2026-03-15 | 5/250 |
|
|
[考研] 北科281學(xué)碩材料求調(diào)劑 +5 | tcxiaoxx 2026-03-20 | 5/250 |
|
|
[考研] 求調(diào)劑 +3 | eation27 2026-03-20 | 3/150 |
|
|
[論文投稿]
申請回稿延期一個月,編輯同意了。但系統(tǒng)上的時間沒變,給編輯又寫郵件了,沒回復(fù)
10+3
|
wangf9518 2026-03-17 | 4/200 |
|
|
[碩博家園] 湖北工業(yè)大學(xué) 生命科學(xué)與健康學(xué)院-課題組招收2026級食品/生物方向碩士 +3 | 1喜春8 2026-03-17 | 5/250 |
|
|
[考研] 085601求調(diào)劑 +4 | Du.11 2026-03-16 | 4/200 |
|
|
[考研] 321求調(diào)劑 +5 | 大米飯! 2026-03-15 | 5/250 |
|