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tepid至尊木蟲 (職業(yè)作家)
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Chem Rev最新關(guān)于水凝膠的綜述Hydrogels for Protein Delivery 已有2人參與
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文獻(xiàn)主要介紹關(guān)于水凝膠在Protein delivery中的應(yīng)用,從水凝膠的制備,材料的分類做了綜述,當(dāng)然包括很多蟲蟲關(guān)注的智能水凝膠。 CONTENTS 1. Introduction 1.1. Pharmaceutical Proteins and Delivery Issues 1.2. Particulate Protein Delivery Systems 1.2.1. Microspheres and Nanoparticles 1.2.2. Lipid-Based Delivery Systems 1.3. Hydrogels for Sustained DeliveryGeneral Features 2. Cross-Linking Methods for in Situ Forming Hydrogels 2.1. Physical Cross-Linking 2.1.1. Inclusion Complexes 2.1.2. Stereocomplexation 2.1.3. Peptide Interactions 2.2. Chemical Cross-Linking 2.2.1. Photopolymerization 2.2.2. Michael Addition 2.2.3. Native Chemical Ligation 2.2.4. Click Chemistry 3. Hydrogels Based on Natural Polymers 3.1. Polysaccharides 3.1.1. Alginate 3.1.2. Chitosan 3.1.3. Dextran 3.1.4. Hyaluronic Acid 3.2. Protein-Based Hydrogels 3.2.1. Collagen and Gelatin 3.3. DNA-Based Hydrogels 4. Smart Hydrogels 4.1. Stimuli-Sensitive Polymers for in Situ Gelling Systems 4.1.1. Temperature-Sensitive Hydrogels 4.1.2. pH Sensitive Hydrogels 4.1.3. pH/Temperature-Sensitive Hydrogels 4.2. Other Stimuli Responsive Polymers 4.2.1. Biomolecule Sensitive Hydrogels 4.2.2. Drug-Sensitive Hydrogels 4.2.3. Light-Sensitive, Electrosensitive, and Magnetic Field Sensitive Hydrogels 4.3. Nanogels 5. Gel Characteristics and Protein Release Mechanisms 5.1. Mechanical Properties 5.2. Mesh Size 5.3. Protein Release Mechanisms: Background 5.4. Diffusion-Controlled Release 5.5. Degradation-Controlled Release 5.6. Modulating Protein Release 5.7. Methods To Measure Release Kinetics 5.8. Protein Stability 6. Hydrogel/Protein Formulations under Preclinical and Clinical Development 7. Conclusions |
6點(diǎn)7點(diǎn)8點(diǎn)。。。 |

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