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ludou2009銀蟲 (正式寫手)
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推薦一篇2011年發(fā)在Nano Letter上的基于表面等離激元共振效應(yīng)的生物化學(xué)傳感器 已有1人參與
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ABSTRACT: In this work, we report the design, fabrication, and characterization of novel biochemical sensors consisting of nanoscale grooves and slits milled in a metal film to form twoarm, three-beam, planar plasmonic interferometers. By integrating thousands of plasmonic interferometers per square millimeter with a microfluidic system, we demonstrate a sensor able to detect physiological concentrations of glucose in water over a broad wavelength range (400−800 nm). A wavelength sensitivity between 370 and 630 nm/RIU (RIU, refractive index units), a relative intensity change between ~103 and 106 %/RIU, and a resolution of ~3 × 10−7 in refractive index change were experimentally measured using typical sensing volumes as low as 20 fL. These results show that multispectral plasmonic interferometry is a promising approach for the development of high-throughput, real-time, and extremely compact biochemical sensors. |
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