 |
 |
 |
 |
 |
 |
||
 |
 |
 |
 |
 |
| 2 | 1/1 | 返回列表 |
| 查看: 325 | 回復(fù): 1 | ||||||||
| 【懸賞金幣】回答本帖問題，作者kittydog將贈送您 50 個金幣 | ||||||||
kittydog木蟲 (小有名氣)
|
[求助]
求助21077004/ B070601 基金摘要
|
|||||||
|
回復(fù)此樓» 猜你喜歡
276求調(diào)劑。有半年電池和半年高分子實習(xí)經(jīng)歷
已經(jīng)有8人回復(fù)
-
接收2026碩士調(diào)劑(學(xué)碩+專碩)
已經(jīng)有3人回復(fù)
-
材料與化工考研調(diào)劑
已經(jīng)有3人回復(fù)
-
081700 調(diào)劑 267分
已經(jīng)有3人回復(fù)
-
一志愿重慶大學(xué)085700資源與環(huán)境，總分308求調(diào)劑
已經(jīng)有3人回復(fù)
-
336化工調(diào)劑
已經(jīng)有4人回復(fù)
-
08工學(xué)調(diào)劑
已經(jīng)有10人回復(fù)
-
263求調(diào)劑
已經(jīng)有6人回復(fù)
-
298求調(diào)劑
已經(jīng)有8人回復(fù)
-
考研化學(xué)308分求調(diào)劑
已經(jīng)有6人回復(fù)
【答案】應(yīng)助回帖
|
高暴露地區(qū)母嬰血液中多溴聯(lián)苯醚代謝產(chǎn)物及潛在風(fēng)險研究 基本信息 批準(zhǔn)號20807003 項目名稱高暴露地區(qū)母嬰血液中多溴聯(lián)苯醚代謝產(chǎn)物及潛在風(fēng)險研究 項目類別青年科學(xué)基金項目 申請代碼B070704 項目負(fù)責(zé)人邱興華 負(fù)責(zé)人職稱研究員 依托單位北京大學(xué) 研究期限2009-01-01 到 2011-12-31 資助經(jīng)費20.0000（萬元） 項目摘要 中文摘要 環(huán)境污染物暴露是影響人體健康的重要因素，而建立污染物暴露與健康效應(yīng)的聯(lián)系是控制污染物排放以保護(hù)人體健康的理論依據(jù)。本研究一方面選擇典型的污染區(qū)域（電子垃圾拆解場），篩選典型的污染物并評價其健康效應(yīng)。研究發(fā)現(xiàn)電子垃圾場地區(qū)人體血液中電子垃圾相關(guān)的持久性有機(jī)污染物如PCBs、低溴代PBDEs、BB-153、Dechlorane Plus等均顯著高于對照地區(qū)，是后者的2-8倍。與此相應(yīng)的是，電子垃圾場地區(qū)人體遺傳損傷顯著高于對照地區(qū)，體內(nèi)氧化應(yīng)激、免疫功能等由污染物導(dǎo)致的健康效應(yīng)均顯示該地區(qū)人群具有更高的健康風(fēng)險包括腫瘤風(fēng)險。另外一方面以健康效應(yīng)（神經(jīng)管畸形）為出發(fā)點，研究持久性有機(jī)污染物暴露的與神經(jīng)管畸形發(fā)生的關(guān)系，發(fā)現(xiàn)當(dāng)暴露于較高濃度PAHs等污染物時，胎兒發(fā)生神經(jīng)管畸形的風(fēng)險增加并具有顯著的劑量-反應(yīng)關(guān)系。本研究表明，污染物尤其是持久性有機(jī)污染物暴露對人體健康有重要影響；進(jìn)一步的分子水平的機(jī)理研究將有利于揭示污染物暴露的健康效應(yīng)機(jī)制。 中文主題詞電子垃圾拆解場，持久性有機(jī)污染物，健康效應(yīng)，腫瘤風(fēng)險，神經(jīng)管畸形 英文摘要 Human's exposure to environmental pollutants and the consequent health effects are important scientific issues. In this project we chose electronic-waste (e-waste) recycling site as typical polluted region and measured persistent organic pollutants in human blood to explore their health effects. We found that e-waste related pollutants, inlcuding PCBs, lower brominated PBDEs, BB-153, and Dechlorane Plus in blood samples from people working or living in the e-waste site were 2-8 folds higher than in those from a control region. Correspondingly, biomarkers of health effects, including geneic damage, oxidative stress, immune function, and so on, all insinuated a higher health risk especially the risk of tumour for people working or living in the e-waste site. On the other hand, we explored the risk factors of a certain health outcome, i.e., neural tube defects, by measuring persistent organic pollutants including PBDEs, PCBs, PAHs, and pesticides in placentas as indicator of fetus/infant prenatal exposure. We found that when exposed to higher levels of PAHs and some pesticides, the risk of neural tube defects significantly increased with dose-response relationship. These studies provided a preliminary view on the relationship between exposure to pollutants and the health effects, and further research on molecular level is warranted to reveal the mechanism of health effects caused by pollutants. 英文主題詞e-waste recycling site，persistent organic pollutants, health effects, risk of tumour, neural tube defects |
2樓2014-04-15 12:09:52
相關(guān)版塊跳轉(zhuǎn)
我要訂閱樓主 kittydog 的主題更新
| 2 | 1/1 | 返回列表 |
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研]
 材料與化工考研調(diào)劑
+3
|
孅華 2026-03-22 | 3/150 |
|
|---|---|---|---|---|
|
[考研]
 一志愿東華大學(xué)化學(xué)070300，求調(diào)劑
+7
|
2117205181 2026-03-21 | 8/400 |
|
|
|
[考研] 293求調(diào)劑 +3 | 濤濤Wjt 2026-03-22 | 5/250 |
|
|
|
[考研] 石河子大學(xué)（211、雙一流）碩博研究生長期招生公告 +3 | 李子目 2026-03-22 | 3/150 |
|
|
|
[考研] 305分求調(diào)劑（食品工程） +4 | Sxy112 2026-03-21 | 6/300 |
|
|
|
[考研] 求調(diào)劑 +3 | 13341 2026-03-20 | 3/150 |
|
|
|
[考研] 求調(diào)劑 +3 | .m.. 2026-03-21 | 4/200 |
|
|
|
[考研] 求調(diào)劑 +3 | 白QF 2026-03-21 | 3/150 |
|
|
|
[考研] 材料學(xué)學(xué)碩080502 337求調(diào)劑-一志愿華中科技大學(xué) +4 | 順順順mr 2026-03-18 | 5/250 |
|
|
|
[考研] 085601調(diào)劑 358分 +3 | zzzzggh 2026-03-20 | 4/200 |
|
|
|
[考研] 一志愿重慶大學(xué)085700資源與環(huán)境專碩，總分308求調(diào)劑 +3 | 墨墨漠 2026-03-18 | 3/150 |
|
|
|
[考研] 304求調(diào)劑 +6 | 曼殊2266 2026-03-18 | 6/300 |
|
|
|
[考研] 274求調(diào)劑 +10 | S.H1 2026-03-18 | 10/500 |
|
|
|
[考研] 321求調(diào)劑 +9 | 何潤采123 2026-03-18 | 11/550 |
|
|
|
[考研] 材料學(xué)求調(diào)劑 +4 | Stella_Yao 2026-03-20 | 4/200 |
|
|
|
[考研] 材料與化工專碩調(diào)劑 +7 | heming3743 2026-03-16 | 7/350 |
|
|
|
[考研] 085601材料工程專碩求調(diào)劑 +10 | 慕寒mio 2026-03-16 | 10/500 |
|
|
|
[考研] 085600材料與化工調(diào)劑 324分 +10 | llllkkkhh 2026-03-18 | 12/600 |
|
|
|
[考研] 收復(fù)試調(diào)劑生 +4 | 雨后秋荷 2026-03-18 | 4/200 |
|
|
|
[考研] 一志愿蘇州大學(xué)材料工程（085601）專碩有科研經(jīng)歷三項國獎兩個實用型專利一項省級立項 +6 | 大火山小火山 2026-03-16 | 8/400 |
|