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1 Tumor vessel obstruction by intraluminal endothelial cells was recently reported in response to γ-secretase inhibitor treatment in both an orthotopic renal cell carcinoma and a VEGF-driven rabbit h ind limb angiogenesis model. 2 In contrast, however, a recent study demonstrated reduced microvascular occlusion and the modulation of vasoconstriction following inhibition of Dll4-Notch signaling during post-angiogenic remodeling in retinal angiogenesis. [ Last edited by yin198716 on 2013-1-8 at 16:29 ] |
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李氏氏
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220chengeng: 金幣+1, 感謝應(yīng)助 2013-01-09 14:42:34
sltmac: 金幣+5, 翻譯EPI+1 2013-03-06 12:03:13
220chengeng: 金幣+1, 感謝應(yīng)助 2013-01-09 14:42:34
sltmac: 金幣+5, 翻譯EPI+1 2013-03-06 12:03:13
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1 Tumor vessel obstruction by intraluminal endothelial cells was recently reported in response to γ-secretase inhibitor treatment in both an orthotopic renal cell carcinoma and a VEGF-driven rabbit H ind limb angiogenesis model. 2 In contrast, however, a recent study demonstrated reduced microvascular occlusion and the modulation of vasoconstriction following inhibition of Dll4-Notch signaling during post-angiogenic remodeling in retinal angiogenesis. 1 最近有報道管腔內(nèi)的內(nèi)皮細(xì)胞阻塞腫瘤血管回應(yīng)了γ-分泌酶抑制劑在原位腎細(xì)胞癌和血管內(nèi)皮生長因子驅(qū)動的肢體血管新生模型中的治療方法。 2然而，與此相反，最近的一項研究表明在后血管重塑視網(wǎng)膜血管生成過程中減少的微血管阻塞和血管收縮調(diào)制伴對于Dll4-Notch信號有抑制作用。 |
2樓2013-01-09 11:27:45
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