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yin198716新蟲 (正式寫手)
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1 A recent report demonstrated that chronic Dll4 blockade induced vascular proliferation in liver of mice, rats, and monkeys with associated hepatocellular changes, as well as the development of subcutaneous vascular lesions in rats, referred to as neoplasia. 2 It will be important to assess whether similar pathological changes are observed with doses of anti-Dll4 antibody that are clinically relevant. |

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木蟲 (著名寫手)
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1 A recent report demonstrated that chronic Dll4 blockade induced vascular proliferation in liver of mice, rats, and monkeys with associated hepatocellular changes, as well as the development of subcutaneous vascular lesions in rats, referred to as neoplasia. 最近一份報告表明,慢性Dll4阻斷能夠誘發(fā)小鼠、大鼠和猴子肝血管增生,并伴隨肝細(xì)胞改變,以及大鼠皮下血管病變的發(fā)展(稱為瘤)。 2 It will be important to assess whether similar pathological changes are observed with doses of anti-Dll4 antibody that are clinically relevant. 在采用臨床相關(guān)劑量的抗Dll4抗體條件下,考察能否觀察到類似病理變化將十分重要。 |

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