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yin198716新蟲 (正式寫手)
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1 As noted earlier, pericytes represent a specialized mesenchymal cell type (related to smooth muscle cells) with finger-like projections that wrap around the endothelial tubing of blood vessels. In normal tissues, pericytes are known to provide paracrine support signals to the normally quiescent endothelium. 2 For example, Ang-1 secreted by pericytes conveys antiproliferative stabilizing signals that are received by the Tie2 receptors expressed on the surface of endothelial cells; some pericytes also produce low levels of VEGF that serve a trophic function in endothelial homeostasis. Pericytes also collaborate with the endothelial cells to synthesize the vascular basement membrane that anchors both pericytes and endothelial cells and helps vessel walls to withstand the hydrostatic pressure of blood flow. |
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zjpa
木蟲 (正式寫手)
- 翻譯EPI: 17
- 應(yīng)助: 13 (小學(xué)生)
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- 專業(yè): 藥物分析
【答案】應(yīng)助回帖
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sltmac: 金幣+1 2013-01-19 08:46:30
yin198716: 金幣+2, 翻譯EPI+1, ★有幫助 2013-01-21 14:09:33
sltmac: 金幣+1 2013-01-19 08:46:30
yin198716: 金幣+2, 翻譯EPI+1, ★有幫助 2013-01-21 14:09:33
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1.如前所述，周細(xì)胞代表一個(gè)專門的間充質(zhì)細(xì)胞類型（與平滑肌細(xì)胞相關(guān)），具有環(huán)繞包裹于血管的內(nèi)皮管的指狀突起。在正常組織中，我們知道周細(xì)胞向正常靜息內(nèi)提供旁分泌的支持信號(hào)。 2.例如，周細(xì)胞分泌的Ang-1，傳送所接收的內(nèi)皮細(xì)胞表面上表達(dá)的Tie2受體的抗惡性細(xì)胞增生穩(wěn)定信號(hào)；一些周細(xì)胞也產(chǎn)生為內(nèi)皮組織自身平衡提供營養(yǎng)機(jī)能的低水平VEGF。周細(xì)胞與內(nèi)皮細(xì)胞共同協(xié)作合成集合周細(xì)胞和內(nèi)皮細(xì)胞血管基底膜，并有助于血管壁承受血流量的液體靜壓。 |
2樓2013-01-18 22:30:18
3樓2013-01-19 10:13:38
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