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zhongtong鐵桿木蟲(chóng) (正式寫(xiě)手)
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[求助]
求翻譯一小段,要求信雅達(dá)必備!
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Unraveling the genetics of complex diseases can be enhanced by focusing on underlying risk factors. For example, studies on lipoproteins and blood pressure have been shown to correlate well with the risk of vascular disease. Insights into the pathogenesis of breast cancer may be informed in a similar way using MD because both may be determined by similar genetic variants. In fact, the number of genetic and environmental factors influencing an intermediate such as MD is likely smaller than that influencing the endpoint, namely breast cancer. Consequently, studies to identify genes for MD could be more powerful and efficient than those for breast cancer. 注:MD為疾病某一表型縮寫(xiě),不用翻譯 |
木蟲(chóng) (著名寫(xiě)手)
| 集中研究潛在的疾病風(fēng)險(xiǎn)因子,可以更好地揭示復(fù)雜疾病的遺傳機(jī)理。譬如,研究已經(jīng)表明脂蛋白和血壓與血管疾病風(fēng)險(xiǎn)之間具有良好的相關(guān)性。類(lèi)似地,可以利用MD來(lái)探析乳腺癌的發(fā)病機(jī)理,因?yàn)閮烧呖赡苡上嗨频倪z傳變異決定。事實(shí)上,影響諸如MD之類(lèi)的中期癥狀的遺傳和環(huán)境因素,在數(shù)量上可能要少于影響終末期癥狀(即乳腺癌)的因素。因此,研究鑒定MD的基因,可能比研究乳腺癌基因更強(qiáng)大有效。 |

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