 |
 |
 |
 |
 |
 |
||
 |
 |
 |
 |
 |
| 1 | 1/1 | 返回列表 |
| 查看: 409 | 回復(fù): 0 | |||
chao1.zhang銀蟲 (小有名氣)
|
[交流]
羅氏抗體-藥物偶合新藥上市，又一系列重磅開始？
|
|
Trastuzumab emtansine (INN; in the United States, ado-trastuzumab emtansine, trade name Kadcyla) is an antibody-drug conjugate consisting of the monoclonal antibody trastuzumab (Herceptin) linked to the cytotoxic agent mertansine (DM1).Trastuzumab alone kills cancer cells by binding to the HER2 receptor. The conjugate includes emtansine, which enters the cell and destroys the cell by binding to tubulin.Because monoclonal antibodies target HER2, and HER2 is only expressed in breast cancer cells, the conjugate delivers the toxin emtansine only to breast cancer cells.Meet the Bay Area's next blockbuster drug: T-DM1, a breast cancer-fighting treatment developed by Genentech Inc., leads the early Class of 2013 drugs seeking Food and Drug Administration approval. The FDA's decision date is Feb. 26. In the EMILIA clinical trial of women with advanced HER2 positive breast cancer who were already resistant to trastuzumab alone, it improved survival by 5.8 months compared to the combination of lapatinib and capecitabine. Based on that trial, the U.S. FDA approved marketing on February 22, 2013. |
回復(fù)此樓» 猜你喜歡
細(xì)胞死亡新方式：銅死亡
已經(jīng)有9人回復(fù)
-
醫(yī)學(xué)類教育學(xué)類 簡單易中的中文核心
已經(jīng)有1人回復(fù)
-
藥物學(xué)論文潤色/翻譯怎么收費?
已經(jīng)有52人回復(fù)
-
對作者單位沒有歧視的核心期刊
已經(jīng)有1人回復(fù)
-
導(dǎo)師咨詢
已經(jīng)有5人回復(fù)
-
膿毒癥（盲腸結(jié)扎）
已經(jīng)有22人回復(fù)
-
博導(dǎo)推薦
已經(jīng)有2人回復(fù)
-
哪里做甘氨酸受體與配體結(jié)合率的試驗
已經(jīng)有0人回復(fù)
-
關(guān)于SCI雜志發(fā)表掛名
已經(jīng)有32人回復(fù)
相關(guān)版塊跳轉(zhuǎn)
我要訂閱樓主 chao1.zhang 的主題更新
| 1 | 1/1 | 返回列表 |
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 304求調(diào)劑 +4 | 曼殊2266 2026-03-18 | 4/200 |
|
|---|---|---|---|---|
|
|
[考研] 085700資源與環(huán)境308求調(diào)劑 +7 | 墨墨漠 2026-03-18 | 7/350 |
|
|
|
[考研] 329求調(diào)劑 +5 | 想上學(xué)吖吖 2026-03-19 | 5/250 |
|
|
|
[考研] 材料學(xué)碩318求調(diào)劑 +5 | February_Feb 2026-03-19 | 5/250 |
|
|
|
[考研] 307求調(diào)劑 +9 | 冷笙123 2026-03-17 | 9/450 |
|
|
|
[考研] 294求調(diào)劑材料與化工專碩 +14 | 陌の森林 2026-03-18 | 14/700 |
|
|
[考研] 生物學(xué)調(diào)劑招人！�。� +3 | 山海天嵐 2026-03-17 | 4/200 |
|
|
|
[考博] 申博26年 +3 | 八6八68 2026-03-19 | 3/150 |
|
|
|
[考研] 【考研調(diào)劑】化學(xué)專業(yè) 281分，一志愿四川大學(xué)，誠心求調(diào)劑 +5 | 吃吃吃才有意義 2026-03-19 | 5/250 |
|
|
|
[考研] 一志愿福大288有機化學(xué)，求調(diào)劑 +3 | 小木蟲200408204 2026-03-18 | 3/150 |
|
|
|
[考研] 346求調(diào)劑[0856] +3 | WayneLim327 2026-03-16 | 6/300 |
|
|
|
[考研] 08工科 320總分 求調(diào)劑 +5 | 梨花珞晚風(fēng) 2026-03-17 | 5/250 |
|
|
|
[考研] 268求調(diào)劑 +6 | 簡單點0 2026-03-17 | 6/300 |
|
|
|
[考研] 334求調(diào)劑 +3 | 志存高遠(yuǎn)意在機?/a> 2026-03-16 | 3/150 |
|
|
|
[考博] 26博士申請 +3 | 1042136743 2026-03-17 | 3/150 |
|
|
|
[考研] 268求調(diào)劑 +8 | 一定有學(xué)上- 2026-03-14 | 9/450 |
|
|
|
[考研] 考研化學(xué)學(xué)碩調(diào)劑，一志愿985 +4 | 張vvvv 2026-03-15 | 6/300 |
|
|
|
[考研] 考研調(diào)劑 +3 | 淇ya_~ 2026-03-17 | 5/250 |
|
|
|
[考研] 中科大材料專碩319求調(diào)劑 +3 | 孟鑫材料 2026-03-13 | 3/150 |
|
|
|
[考研] 招收0805（材料）調(diào)劑 +3 | 18595523086 2026-03-13 | 3/150 |
|