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yin198716新蟲 (正式寫手)
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| The differential expression between tumor and normal vessels likely explains the preferential targeting of Dll4-expressing tumor endothelial cells in preclinical tumor models. However, clinical development of Dll4 inhibitors requires careful evaluation of possible adverse effects to establish a formal therapeutic index. |

木蟲 (小有名氣)
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The differential expression between tumor and normal vessels likely explains the preferential targeting of Dll4-expressing tumor endothelial cells in preclinical tumor models. 腫瘤和正常血管中的表達差異,可能解釋了在臨床前腫瘤模型中 Dll4表達型腫瘤內(nèi)皮細胞的優(yōu)先靶向性。 However, clinical development of Dll4 inhibitors requires careful evaluation of possible adverse effects to establish a formal therapeutic index. 盡管如此,Dll4抑制劑的臨床發(fā)展仍需要仔細地評估各種可能的副作用以建立一套正式的治療指標。 參考 |

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