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zhtear99鐵桿木蟲 (著名寫手)
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[交流]
科學(xué)家測序了在加拿大出土的約有70萬年的冷凍馬骨化石 已有3人參與
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原文鏈接http://medcitynews.com/2013/06/s ... nada/#ixzz2XfYlkznH
Small pieces of a horse's foot bone that were frozen for approximately 700,000 years in the Yukon Territory of Canada have yielded the oldest genome sequence of any species to date. 加拿大育空地區(qū)冷凍保存約70萬年的馬的小塊足骨化石經(jīng)測序，證實其基因序列是目前所 Scientists unearthed the bone fragments from the Artic permafrost in 2003 and dated the fossils to be between 560,000 - 780,000 years old. Using mass spectroscopy, they found that collagen and other proteins had survived since the Middle Pleistocene and so decided to see if DNA had also endured. 科學(xué)家于2003年在北極凍土中挖掘的足骨化石片段，距今已經(jīng)有56~78萬年了。通過質(zhì)譜檢測，科學(xué)家們發(fā)現(xiàn)其中的膠原蛋白和其他一些蛋白從中更新世存活至今，于是科學(xué)家們決定檢測一下（化石中）是否也有DNA。 It had, and the resulting genome is nearly ten times older than any DNA previously sequenced, thus "breaking the time barrier" for the age of DNA viable for such analysis, said study author Eske Willerslev of the University of Copenhagen at a press conference in Helsinki on Wednesday. 哥本哈根大學(xué)的研究作者Eske Willerslev在赫爾辛基周三的新聞發(fā)布會上講道：（研究）結(jié)果顯示，（該足骨化石中）確實存在DNA，且該DNA比之前測序過的任何DNA都古老將近10倍，這項可行分析打破了DNA存在的時間界限。 While the cold and dry conditions of the permafrost helped keep the DNA intact, the authors also perfected techniques for handling and analyzing the ancient DNA: reports Nature:"They also combined DNA sequencing techniques to get maximum DNA coverage — using routine next-generation sequencing with single-molecule sequencing in which a machine directly reads the DNA without the need to amplify it up which can lose some DNA sequences". 除凍土的干、冷特性有助于保持DNA的完整性外，作者也強調(diào)了日臻完善的技術(shù)對于處理和分析古老DNA的重要性。Nature雜志報道稱“為了獲取更大范圍的DNA序列，研究者同時結(jié)合了DNA測序技術(shù)——采用常規(guī)的下一代測序技術(shù)和單分子測序技術(shù)，機器可直接讀出DNA的序列。該方法不需要擴增，且不會丟失DNA序列。 The researchers predict that future ancient DNA studies could go even further back in time-- "most likely up to a million years" said Ludovic Orlando, a scientist at the University of Copenhagen and co-author on the study. Such a deep look into the evolutionary past "obviously offers great perspective as to the level of detail with which we could reconstruct our own origins and the evolutionary history of almost every single species living on the planet," he said. 研究者預(yù)言，關(guān)于古老DNA的研究在將來會更進一步，在時間上會追溯的更早。哥本哈根大學(xué)的科學(xué)家，同時也是這項研究是合作者Ludovic Orlando說：“時間上可能會追溯到百萬年前。而且，對于進化的如此深度的研究為重建我們的起源和研究這個星球上居住的任何物種的進化歷史都提供了很多細節(jié)上的見解，具有很大的前景�！� The study was published in Nature in Wednesday. 這項研究將發(fā)表在周三的Nature雜志上。 This article originally appeared in MIT Technology Review. 這篇文章最初是發(fā)表在麻省理工學(xué)院科技評論雜志上。 ——June 29, 2013 1:13 pm by Young, Susan Read more: http://medcitynews.com/2013/06/s ... nada/#ixzz2XgxHLHxG P.S. 相關(guān)中文報道見http://tech.ifeng.com/discovery/ ... 28/26898880_0.shtml 紅色部分的翻譯不太確定，歡迎大家糾錯和指教哈~ [ Last edited by zhtear99 on 2013-6-30 at 17:53 ] |
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