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yin198716新蟲 (正式寫手)
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| The stabilization of the newly formed vessel and the main-tenance of the existing vasculature are late events in the angiogenic process.Blood flow is critically importat for determining the vessel fate [vessels with high flow widen, while vessels with low flow regress, although recent advance of vascular biology strongly argues for the autonomous fate control achieved by blood vessels. More recently, Chen et al. have demonstrated that lymphatic endothelial and vessel phenotype are negatively regulated by blood flow and that changes in hemodynamic forces can reprogram lymphatic vessels to blood vessels in postnatal life. |

木蟲 (知名作家)
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個(gè)人拙見 非專業(yè)化翻譯,僅供參考: 新形成血管的穩(wěn)定性和生成后血管的維持是血管生成過程中的晚期事件,血流量在決定血管的命運(yùn)方面起著關(guān)鍵性的作用。盡管血管生物學(xué)的最新進(jìn)展強(qiáng)烈主張血管的自主命運(yùn)控制理論,但血管中的高血流量會(huì)使新生血管變寬,而如果新生血管中的血流量低會(huì)使剛生成的血管發(fā)生退化確是個(gè)事實(shí)。最近,陳等人,已經(jīng)證實(shí)淋巴管內(nèi)皮和血管型是受血流量影響而形成的負(fù)調(diào)控機(jī)制,并且即使在生成后期,血流的動(dòng)力學(xué)變化也能夠?qū)е掳l(fā)育系統(tǒng)的重新編程而使得淋巴管轉(zhuǎn)變?yōu)檠堋?br /> 希望對(duì)你有一點(diǎn)點(diǎn)幫助 |
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