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China Novartis Institutes for BioMedical Research Co., Ltd. (CNIBR) has some job vacancies as below. If you have interested in these jobs, please send your resume with no hesitation cause we'll provide you more chance to promote yourself in your field. (Sr.) Investigator, Medicinal Chemistry Investigator, Bioinformatics Investigator II/III, Hair Cell Investigator, Epigenetics of Cancer Drug Discovery Investigator, Developmental Biology Scientist I/II, Cellular Assays Investigator, Computer-Aided Drug Design Clinical Trial Head Head of Scientific Operations For more details, please click our career website: http://careers.novartis.com.cn/vacancies.html To apply this position, please send your resume to sarah.qi@novartis.com When you send your resume to sarah.qi@novartis.com, please notice you know this position information via 小木蟲BBS 諾華（中國）生物醫(yī)學(xué)研究有限公司是諾華全球研發(fā)組織――諾華生物醫(yī)學(xué)研究所（NIBR）的第八個研究基地。我們位于中國上海市張江高科技園區(qū)，將成為諾華在亞洲的主要研究中心，以及除在歐美的研究中心外的最主要的研究中心。我們的研究和探索開發(fā)活動的重點(diǎn)是發(fā)現(xiàn)并開發(fā)創(chuàng)新療法，用于治療在亞洲遠(yuǎn)未達(dá)到醫(yī)藥需求的疾病。我們與從不同之處在于將專注現(xiàn)代藥物的發(fā)現(xiàn)和開發(fā)方法的研究。最初階段，研發(fā)工作將專注在引起中國地方性癌癥的感染原因。我們還將開展臨床試驗(yàn)，進(jìn)行安全性研究，生物標(biāo)志物和檢測分析，表達(dá)譜、生物分析以及轉(zhuǎn)化醫(yī)學(xué)的研究。 隨著公司業(yè)務(wù)的迅速擴(kuò)展，我們熱忱歡迎您的加入。同時我們將提供具有競爭力的薪酬福利待遇以及良好的培訓(xùn)發(fā)展機(jī)會。 NIBR Shanghai NIBR Shanghai is an integrated research center that is part of the Novartis global research and development network. The establishment of this strategic site is a commitment by Novartis to conduct cutting-edge pharmaceutical research in China. Research activities at NIBR Shanghai focus on addressing urgent medical needs in China, particularly infectious causes of cancer endemic to the region. The center also established programs in epigenetics, biomarker development, drug metabolism and preclinical safety to support NIBR local and global R&D projects.Research at NIBR Shanghai is currently focused on discovering new therapies for infectious causes of cancer, such as liver cancer caused by HBV or HCV hepatitis. As the diseases are highly prevalent in the region, some one-third of the 400 million people infected with the hepatitis B virus are in China, with estimates that 300,000 people die from liver cancer in the mainland each year. A Growing and Dynamic Organization China Novartis Institutes for BioMedical Research Co., Ltd. (CNIBR), the legal entity for NIBR Research Center in Shanghai was launched in November 2006 and the start-up Research facilities opened in April 2007. Today, NIBR Shanghai has grown to an organization of about 260 associates including nearly 200 scientists. The research teams are comprised of both returnee scientists from abroad (about 20% of total scientists), and graduates from top tier universities, medical centers, and research institutes in China. Currently the center operates in an office building and two lab facilities in the Zhangjiang Hi-Tech Park. In the same area, the new Novartis Shanghai Campus is under design and construction. The first phase of the project will be completed by the end of 2014. [ Last edited by saliand on 2013-8-7 at 15:17 ] Investigator II Job Purpose Manage projects (with a TA focus), interpret and present information and negotiate an optimal PK/PD strategy for early and late development in liaison with TA-PK Head and appropriate line functions. Responsible for the PK, PK/PD and M&S component of study protocols, reports and project summaries within agreed timeframes and which meet regulatory requirements. Take the lead on appropriate pharmacokinetic /biopharmaceutical studies. Major Accountabilities • Define PK, PK/PD, biopharmaceutical and M&S requirements in project (nonclinical and clinical) development plans and appropriate strategies for global registration. • Analyze, interpret and represent PK, PK/PD and M&S data generated during development and provide guidance. • Proactively manage links with other functions to ensure that pre-clinical and clinical PK/PD information are used optimally. • Directly or indirectly take the lead on appropriate pharmacokinetic/biopharmaceutical studies. • Prepare summary information for internal and external Advisory panels, Investigator meetings and Health Authorities as part of the regulatory approval process. This includes PK/PD components of IND applications in the US, CTX in other countries. • Represent the PK/PD discipline and ensure high quality interactions with various health authorities, external investigators, and various internal Novartis Disease Area experts • Coordinate with appropriate sub-team members and other LF experts and/ or prepare (when needed) summary documentation on drug metabolism and pharmacokinetics as required by ethics committees and HAs (IB, BB, CTA/IND, responses to HAs). • Prepare, compile and review appropriate sections of CTD dossiers /NDA documents. • Contribute to and support continuous improvement initiatives in global pharmacokinetics and partner functions Ideal Background Education: Ph.D. in Pharmaceutical Sciences, or related disciplines (or equivalent degree/knowledge/expertise) Languages: fluent English and Chinese (spoken and written) Experience: 3-4 years of experiences in drug development or a relevant environment [ Last edited by saliand on 2013-10-12 at 17:49 ] |
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Investigator, Computer-Aided Drug Design Job Description: Employ CADD technology in support of drug discovery projects and work close with multidisciplinary drug discovery teams Suggest and develop new approaches leading to the identification of lead and optimization of the small molecule Design and maintain a cutting-edge CADD platform of relevant resources both in terms of software, chemical database and scientific information which will be actively used by the project Minimum Requirements: Ph.D. degree in computational chemistry, computational biology or a relevant field with at least two years industry experience In-depth knowledge and comprehension of CADD in drug discovery A proven track record in the use of standard CADD approaches Experienced in protein modeling, structural analysis, binding site mapping, docking and post-docking analysis, library design/ranking, and virtual screening Demonstrate skills in the fields of molecular dynamics Show know to how in the field of molecular descriptors (knowledge of existing fragment counts, pharmacophore fingerprints and design of new terms), and structure-activity relationships Demonstrated expertise in handling/maintenance of large databases, clustering, QSAR, and ADME optimization |
8樓2013-07-30 17:34:24
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Investigator II/III, Hair Cell Job Description: Explore the molecular mechanism underlying inner ear hair cell development and regeneration Elucidate the molecular mechanism of hair cell differentiation and transdifferentiation, genetic and epigenetic regulation of hair cell development and regeneration Minimum requirements: Ph.D. in Developmental Biology, Cell Biology or related fields or a Medical degree in Otolaryngology, minimal three years postdoc training Strong scientific capabilities as manifested by a strong publication record Previous experience in hearing research is required. Deep understanding of hair cell biology, particularly hair cell development and regeneration as well as hands on experience with primary tissue culture, organotypical culture, small animal surgery and molecular biology are required |
2樓2013-07-30 17:14:24
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Sr. Investigator, Medicinal Chemistry Job Description: Lead a group of medicinal scientists (Ph.D./MS) to support drug discovery research programs Design tool compounds and experiments to support target validity, drive hits to high quality leads and drug candidates by optimization of efficacy, ADME and safety Collaborate with scientists from other platforms in Novartis and external collaborators Minimum Requirements: Ph.D. in synthetic organic or medicinal chemistry; > 5 years of relevant experience in the major pharmaceutical industry or biotechs Experience in identifying hits for difficult targets by exploiting in silico methods, novel chemical libraries and structure based design, oncology and immunology experience as required Proven track record of innovative project contributions including peer-reviewed publications Ability to work independently and ability to collaborate with a multidisciplinary team, excellent oral/written communication and presentation skills [ Last edited by saliand on 2013-7-30 at 17:21 ] |
3樓2013-07-30 17:19:58
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Investigator, Bioinformatics Job Description: Data mining of large scale multi-omics data Integrating multi-omics data for drug discovery and biomarker development Developing useful computational tools and new algorithms for biological research Providing expert data-mining support to drug discovery and translational research Minimum requirements: Ph.D. in bioinformatics, computational biology, mathematics, computer science or other related fields Three or more years of relevant post-graduate research experience in bioinformatics data analysis Independent problem-solving capability Excellent skills in statistical software like R and/or Matlab Excellent programming skills with scripting language such as Perl and Python Experience with next-generation-sequencing data is essential Wide experience in genome-sequencing, ChIP-seq, transcriptomics, and proteomics, compound profiling analysis |
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