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1、Although this study may affirm or expand on available literature, we do not feel that the paper contains sufficient new or novel information to assign a high enough priority in this area, as required for full review. 2、If you look at the Journal guidelines on the web or browse some recent issues, you will see that we are interested in the methodological aspects of medical and health research. While your paper does talk about some important methodological issues, the methods you describe are fairly simple and your approach is based on simulation, which is difficult to generalize. Some of the statements you make regarding the commonly used approaches to treatment allocation seem naive as well. There has been a great deal written on this topic in recent years. From a presentation perspective, there are also some issues with your paper. For example, the logical flow is awkward in places and there are a number of typos in your paper. |

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