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yin198716新蟲(chóng) (正式寫(xiě)手)
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| Lessons learned from the preclinical and clinical development of GSIs may offer some clues for a potential path forward. Since it is generally believed that the outcome of Notch signaling is dependent on context and the degree of activation, it is possible that partial pathway inhibition might ameliorate the toxicities associated with stringent and continuous pathway blockade while maintaining efficacy. |

木蟲(chóng) (正式寫(xiě)手)
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從臨床以及關(guān)于胰島素分泌的發(fā)展的獲得經(jīng)驗(yàn)教訓(xùn)可能為一種可能的方法的前進(jìn)提供線索。因?yàn)楸娝苤琋otch信號(hào)肽的結(jié)果依賴于環(huán)境與激活的程度。部分的途徑的阻遏可能減輕與應(yīng)急性途徑與連續(xù)途徑堵塞有關(guān)的毒性,同時(shí)保持功效,這種想法是可能的。 十分鐘給你翻譯的。。。 |
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