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preexisting functional abilities such as mobility,respiratory function,skin integrity,and nutritional status establish patients'performance condition.Tools such as the Karnofsky, World Heath Organization,and Zubrod scales objectively measure functional abilities.Howerer,the scales measure only physical functional abilities of atients. For patients who recur after initial therapy,response to additional chemothepapy seems to be directly related to the platinum-free interval,which is the time elapsed since the completion of platinum-based therapy without recurrence.Some will be retreated with previously demonstrated tumor-sensitive regimes as well as new drugs in novel combinations or delivery modalities.Responses to subsequent treatments can vary ased on the intensity of previous side effects and residual sequelae. |
鐵桿木蟲 (知名作家)
神蟲浮云

版主 (文壇精英)
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預(yù)先存在的功能性能力,如活動度,呼吸功能,皮膚完整性,以及營養(yǎng)狀況構(gòu)成了患者的身體狀況/條件?ㄊ,世界衛(wèi)生組織和朱布羅德評分尺度等工具客觀地測量功能能力.然而,評分尺度只衡量病人的體格功能性能力。 對于初次治療后復(fù)發(fā)的患者,其他化療療效似乎是直接與停用鉑類藥物化療時間相關(guān),即基于鉑類治療完成后無復(fù)發(fā)經(jīng)厲的時間。除了新藥物新組合或改變給藥途徑外,有些人可以用先前敏感的抗腫瘤藥物再次進(jìn)行治療。機(jī)體對后續(xù)治療的反應(yīng)根據(jù)以前的副作用和殘留后遺癥的強(qiáng)度而有不同。 |

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