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qwliving鐵蟲 (初入文壇)
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[求助]
求助翻譯一段話。中譯英
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| 異位骨化(HO)可導(dǎo)致患肢腫痛、活動受限，影響患者后續(xù)功能恢復(fù)，削弱組織重建，增加后續(xù)外科治療的介入所需花費的費用，發(fā)病率及致殘率高，給社會經(jīng)濟帶來重大影響。HO形成的確切機制尚未明確，多認為與損傷組織及炎性細胞釋放的調(diào)控蛋白誘導(dǎo)間充質(zhì)干細胞（MSCs）向骨、軟骨細胞分化相關(guān)。轉(zhuǎn)化生長因子β（TGF-β）為TGF-β家族的成員，TGF-β信號是誘導(dǎo)MSCs分化為骨、軟骨細胞的關(guān)鍵信號，TGF-β/smad信號通路有很強的的刺激成骨作用。 |
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Silentrest
銅蟲 (小有名氣)
- 應(yīng)助: 4 (幼兒園)
- 金幣: 187.9
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- 帖子: 187
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- 注冊: 2013-11-18
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- 專業(yè): 醫(yī)學(xué)免疫學(xué)
【答案】應(yīng)助回帖
★ ★ ★ ★
真強必勝: 金幣+2, H好 2014-02-14 10:15:34
qwliving(RXMCDM代發(fā)): 金幣+2, 多謝應(yīng)助！ 2014-03-15 23:00:48
真強必勝: 金幣+2, H好 2014-02-14 10:15:34
qwliving(RXMCDM代發(fā)): 金幣+2, 多謝應(yīng)助！ 2014-03-15 23:00:48
| Heterotopic ossification (HO) can lead to limb swelling pain and restricted movement, which would affect the follow-up in patients with functional recovery, weaken the organization reconstruction, increasing the involvement of subsequent surgical treatment costs, morbidity and high morbidity and bring great influence to social economy. The exact mechanisms that how the HO is forming remain unclear. It is believed nowadays that the tissue damage and inflammatory cells release of efflorescence stem cells (MSCs) regulatory proteins induced cell differentiation related to the bone and cartilage. Transforming growth factor beta (TGF - beta) as the members of the family of TGF - beta, TGF - beta signals is the key to induce MSCs to differentiate into bone, cartilage cells signal, TGF - beta/smad signaling pathway has a strong role in stimulating osteogenesis. |
2樓2014-02-13 16:20:37
RXMCDM: 多謝應(yīng)助！ 2014-02-25 20:37:05
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3樓2014-02-23 16:35:31
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