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上海應(yīng)用技術(shù)學院胡隆勝實驗室歡迎你
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本校碩士研究生有一定的調(diào)劑名額，本課題組欲接收報考化學、化學相關(guān)專業(yè)，有制藥工程、有機化學背景的考生優(yōu)先。請有意愿者發(fā)郵件聯(lián)系。 一、調(diào)劑應(yīng)符合的條件 調(diào)劑考生初試成績必須符合其第一志愿報考專業(yè)所在地區(qū)的復(fù)試分數(shù)線，必須考數(shù)學，不考數(shù)學的同學不能接收調(diào)劑。 二、調(diào)劑生政策 調(diào)劑考生（專業(yè)學位除外）均為享有普通獎學金。除享受學校的待遇外（每月500），課題組還提供生活補助（視個人努力程度而定，不過生活是沒什么問題的）。 我校對所有2014年研究生制定了如下優(yōu)惠政策： 1、國家助學金及獎學金全覆蓋，每生每年可獲得國家助學金及獎學金在12000元/年左右（定向生 除外），最高可獲得16000元/年； 2、進入實驗室后，導師將根據(jù)研究生實驗進展情況發(fā)放助研津貼，不低于300元/每月； 3、學生入學后報銷部分差旅費 三、聯(lián)系方式 郵箱：dangguoju2008@163.com 四、導師簡介 胡教授是上海應(yīng)用技術(shù)學院制藥工程方向的兼職教授，在外高橋開公司，生產(chǎn)基地在安徽蕪湖，有比較多的實際經(jīng)驗。下面是胡教授的個人簡歷： Longsheng Hu (胡隆勝） 上海靜安長壽路999弄11號樓13層 手機: 156 0188 5001 Email: Lawrencehulong@gmail.com CORE COMPETENCIES主要能力 • Years of diversified drug product / process development experience: formulation, reformulation for dosage forms of solid, semi-solid (gel and emulsion), liquid, suspensions, ointments多年各種藥物劑型：片劑，液體，懸浮液，膏等的開發(fā)和研究 • Drug delivery system development: transdermal, transbuccal, topical, controlled release多種藥物給藥系統(tǒng)：皮膚透吸，口腔膜透吸，皮膚表面吸收以及緩釋的開發(fā)和研究 • Multiple international publications including scientific papers, patent and patent applications and book chapter多篇論文,專利及專利申請,書章節(jié)的發(fā)表 • Diversified education background in chemistry, chemical engineering and pharmaceutical science化學，化學工程以及藥劑制藥學的綜合學科的教育背景 • Highly organized and effective interpersonal communication skills高度組織和有效的個人交流能力 • Fluent in English and Chinese流利的英文和中文 EDUCATION 教育背景 • Ph.D., Pharm. Science, Rutgers, The State University of New Jersey, Sept. 2003 to July, 2010 (worked as a part-time Ph.D student sponsored by Pfizer and J&J) 博士，美國新澤西州羅格斯大學藥學院 • M.S., Chem. Engr., University of Cincinnati, OH 1992-1996碩士，美國辛辛那提大學化工系 • M.S., Pharm. Science, University of Cincinnati, OH 1994-1996碩士，美國辛辛那提大學藥學院 • M.S., Chem. Engr, Sichuan University of China, China 1985-1988碩士，中國四川大學化工系 • B.S., Chemistry, Electronic University of Sci. & Tech. of China, Chengdu, China 1981-1985本科，中國電子科技大學材料應(yīng)用化學系 CAREER SUMMARY Oct. 2011 to Present, Director of Industrial Development, Sanofi – a French pharmaceutical Company, Shanghai, China。 2011年10月至今，工業(yè)事務(wù)部研發(fā)總監(jiān)，法國賽諾菲藥業(yè)公司，中國上海 • 負責倆個研發(fā)中心實驗室的建立: 配方，工藝，分析實驗室以及倆個研發(fā)團隊的建設(shè) • 負責倆個研發(fā)團隊為中國市場中西處方、非處方藥以及保健品的新產(chǎn)品的立項，研究及開發(fā)至上市. 主要產(chǎn)品包括: 糖尿病藥, 護肝藥-易善福, 小兒助消化藥,女式陰道炎,小兒感冒, 鎮(zhèn)痛藥, 過敏藥，維生素補充劑等. • Responsible for setting up two development centers (lab and pilot labs in Hangzhou & Tangshan) with formulation, processing, and analytical functions • Worked closely with a cross functional team of MKT, BD & Medical in NPD strategy, portfolio development and innovations • Managed with a total of 12 FTCs (4 managers + 8 scientists) in formulation, processing, scale up, technical support to the manufacturing sites and analytical method development and Regulatory for TCM & OTC products in Tangshan site • Developed LRP (1 to 5 yrs) and managed day-to-day operations with annual budget of around 20 m RMB • Developed two teams with good working ethic, professionalism, integrity, GMP/cGMP/ICH and global company compliance mind set • Project initialization and management of more than 20 on-going projects including chemical drugs, TCM, OTC, Rx & Health Food such as liver protecting product Essentiale capsule, Diabetic products, Kids cough & cold liquid and granules, Allegra (180 & 120 mg tablet), Kids Digestive, Women Vaginal Treatment, Ibuprofen, Functional Food & Vitamin Supplements, etc. • Effectively communicated and networked with Sanofi Global Industrial Development and Innovation team to bring global product development ideas to China team • Effectively worked with external companies & KOLs for new product ideas and technologies as well as government recognized agency such as SH CDC for product testing, SFDAs and Dept. of Health to expedite product registration and filing processes • Led the health food development team to gain two approvals of Women MV and Silver MV products from CFDA • Led the TS RA team to successfully renew more than 20 product licenses Dec. 2006-Oct. 2011, Johnson & Johnson Consumer HealthCare Division, Morris Plains, NJ, USA。 2006年12月至2011年10月，美國強生制藥首席科學家，主要從事皮膚藥,生發(fā)藥,抗過敏藥的研究和開發(fā),美國新澤西州。 Principal Scientist • Responsible for leading technical activities in new product development, formulation, reformulation, research, new claims and identifying internal or external new technology for OTC Topical HealthCare franchises including Rogaine (hair regrowth), Neosporin (antibiotic) and Bengay (pain reliever),Zyrtec brands with dosage forms of liquid, suspension, foam, patch, ointment, cream • Formulated a new emulsion based minoxidil prototype for efficacy in vivo study. Took lead in working effectively with internal colleagues at J&J Ethicon R&D to develop methodology and study protocol for conducting mice hair regrowth model study for new minoxidil formulations and worked effectively with J&J patent legal dept. to successfully file two USA patent applications for the new formulations • Took a leading role in working with external companies to develop new liposome encapsulation technologies for topical healthcare minoxidil formulations • Led extensive literature research and worked with medical/clinical and regulatory affair colleagues as well as outside experts in writing documents to Division of Dockets Management, FDA regarding Draft Bioequivalence Guidance on Minoxidil Aerosol, Foam/Topical 5% to request generic manufacturer of minoxidil Foam to conduct comprehensive clinical efficacy and safety studies • Guided junior scientist and supervised three college interns to conduct formulation and research work for Rogaine brand 2002-2006, Pfizer Consumer HealthCare Division, Morris Plains, NJ, USA Senior Scientist美國輝瑞制藥高級科學家，主要從事皮膚藥,生發(fā)藥,抗過敏藥的研究和開發(fā),美國新澤西州。 • Responsible for formulation, reformulation, new product development, research, new claims and identifying internal or external new technology for OTC HealthCare franchise including Benadryl (allergy, anti-itch), Rogaine (hair regrowth), Hydrocortisone, Neosporin (antibiotic), Zyrtec and Bengay (pain reliever) • Worked with a cross-functional team including medical/clinical affair, regulatory, process engineering, analytical, micro, stability, marketing, contract manufacturing to ensure successful clinical trial studies, CMC and NDA filing and the launch of Rogaine (minoxidil) Foam product • Identified Novasome/Liposome technology from an external source and applied it in Lubriderm new product development with therapeutic benefits of reducing itching and minimizing eczema • Reformulated and developed pilot plant and manufacturing scale up processes for Hydrocortizone launch • Led the development of pilot plant and manufacturing scale up processes for new minoxidil gel formulation • Supported the launch of Neosporin Scare Reduction Patch product • Supervised three college interns to conduct formulation and research work for Rogaine brand 1996-2002, Avlon-Rani Corp., Chicago, IL, USA Senior Scientist / Formulation Group Leader 美國芝加哥Avlon-Raani公司科學家及產(chǎn)品開發(fā)組組長 • Responsible for OTC oral and topical drug product and process development for: Cough Suppressant (Dextromethorphan HBr), Nasal Decongestant (Phenylephrine HCl), Expectorant (Guaifensin), Pain Reliever (Ibuprofen, Ketoprofen), Medicated Throat Lozenges (menthol, benzocaine), Vitamin A, B, C and E, medicated skin care products such as acne treatment, etc. in the dosage forms of solid, liquid/suspension, emulsion and liposome • Supervised three formulators 1992-996, University of Cincinnati, Cincinnati, OH, USA 美國辛辛那提大學化工和藥學院研究生 ● Graduate student in Chemical Engineering and Pharmaceutical Science ● Conducted research in preparation and characterization of prolonged release of Chloroprophenpyridamine tablet using wet granulation 1988-1992, Yunnan Institute of Technology, Kunming, Yunnan, China Lecturer of Chemical Engineering Dept. 講師，教研室主任, 云南工學院化工系 • 教化工熱力學,科技英語 • 管理教研室的課程安排等 Professional Trainings ▪ GMP, cGMP, Medical Device, CMC, NDA, and ANDA/SNDA ▪ Project Management, Leadership Behaviour and Business Writing courses ▪ Patent Law, Emulsion / Suspension Technology, and FDA CTD/CMC format courses Publications ▪ Longsheng Hu, Virginia Streusand Goldman, Josephine A Minerva, Susan Wendling: Hair growth and/or regrowth compositions. McNeil-PPC Sep, 6 2012: US Patent 20120225898 ▪ Longsheng Hu, Virginia Streusand Goldman, Josephine A Minerva, Susan Wendling: Hair growth and/or regrowth compositions. McNeil-PPC Sep, 6 2012: US Patent 20120225897 ▪ Longsheng Hu, Virginia Streusand Goldman, Josephine A Minerva, Susan Wendling: Hair growth and/or regrowth compositions. McNeil-PPC Sep, 6 2012: US Patent 20120225897 ▪ Bozena Michniak-Kohn, Longsheng Hu, Enhanced Transbuccal Drug Delivery System and Compositions, US Provisional Patent Application 61/386.001 and International Application No. PCT/US2011/001645, Sept. 23, 2011 ▪ Ran Wei, Laurent Simon, Longsheng Hu, Bozena Michniak-Kohn, Effects of Iontophoresis and Chemical Enhancers on the Transport of Lidocaine and Nicotine Across the Oral Mucosa, Pharm Res 29(4):961-971 (2012) ▪ Sérgio M C SM Silva, Longsheng Hu,Bozena B BB Michniak-Kohn, A combination of nonionic surfactants and iontophoresis to enhance the transdermal drug delivery of ondansetron HCl and diltiazem HCl. Eur J Pharm Biopharm 80(3):663-73 (2012) ▪ Longsheng Hu, Sérgio MC Silva,Bozena B Michniak-Kohn, Transdermal and transbuccal drug delivery systems: Enhancement using iontophoretic and chemical approaches Int J Pharm 421(1):53-62 (2011) ▪ Longsheng Hu, B.B. Michniak-Kohn, Enhanced Transbuccal Delivery of Ondansetron HCl, US Provisional Patent Application, 2010 ▪ Longsheng Hu, B.B. Michniak-Kohn, Enhanced Transbuccal Delivery of Ondansetron HCl, International J. of Pharm., 404 (2011) 66-74 ▪ Longsheng Hu, Virginia Streusand Goldman, Josephine A Minerva, Susan Wendling: Methods of Reducing Hair Loss and/or Facilitating Hair Growth and/or Regrowth. Mcneil-Ppc Jun, 16 2011: US 20110144142 ▪ Longsheng Hu, Virginia Streusand Goldman, Josephine A Minerva, Susan Wendling: Hair Growth and/or Regrowth Compositions. Mcneil-Ppc Jun, 16 2011: US 20110144141 ▪ Longsheng Hu, P. Batheja, V. Meidan, B. B. Michniak-Kohn, Chapter 4, Iontophoretic Transdermal Drug Delivery, Handdbook of Non-Invasive Drug Delivery Systems, Elsevier, Page 95-114, 2010 ▪ P. Batheja, D. Kaushik, Longsheng Hu and B.B Michniak-Kohn, Transdermal Iontophoresis, Transdermal Delivery, Drug Delivery, Pages 46-48, 2007 ▪ Longsheng Hu, B. B. Michniak-Kohn, Enhanced In Vitro Transbuccal Delivery of Ondansetron HCl, accepted for 2010 AAPS Poster Presentation ▪ Longsheng Hu, B. B. Michniak-Kohn, , A Comparison of In Vitro Transdermal and Transbuccal Drug Delivery Systems using Nicotine Hydrogen Tartrate, accepted for 2010 AAPS Poster Presentation ▪ Longsheng Hu, B. B. Michniak-Kohn, The Effects of Chemical Enhancers and Iontophoresis on In Vitro Transdermal Delivery of Lidocaine HCl, accepted for 2010 AAPS Poster Presentation ▪ S.M.C. Silva, Longsheng Hu, J.J.S. Sousa, A.C.C. Pais, B. Michniak-Kohn, Enhancement strategies to improve the transdermal drug delivery of ondansetron hydrochloride: a combination of chemical penetration enhancers with iontophoresis, accepted for 2010 AAPS Poster Presentation ▪ S.M.C. Silva, Longsheng Hu, J.J.S. Sousa, A.C.C. Pais, B. Michniak-Kohn, Non ionic surfactants as chemical permeation enhancers for the transdermal of diltiazem hydrochloride: in vitro permeation studies and cytotoxicity assessment, accepted for 2010 AAPS Poster Presentation ▪ Ali N Syed, Wagdi W Habib, Longsheng Hu: Hair brightening system. Avlon Dec, 28 1999: US Patent 6007585 歡迎對制藥工程有興趣的青年報考研究生。 |
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