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jiangyumin2鐵桿木蟲 (著名寫手)
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baiyuefei
版主 (文學(xué)泰斗)
風雪
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【答案】應(yīng)助回帖
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abrication and cyto-compatibility of Fe3O4/SiO2/graphene-CdTe QDs/CS nanocomposites for drug delivery. 作者:Ou, Jun; Wang, Fang; Huang, Yuanjie; Li, Duosheng; Jiang, Yuming; Qin, Qing-Hua; Stachurski, Z H; Tricoli, Antonio; Zhang, Tina Colloids and surfaces. B, Biointerfaces 卷:117 頁:466-72 DOI:10.1016/j.colsurfb.2013.12.003 出版年:2014-May-1 (Epub 2013 Dec 11) 摘要 Synthesis of magnetic Fe3O4/SiO2/graphene-CdTe QDs/chitosan nanocomposites (FGQCs) is investigated with respect to their potential of improving the drug loading content above that of magnetic/fluorescent bifunctional nanocomposites. To evaluate the performance of the FGQCs, their surface morphology was thoroughly assessed. The in vitro interaction between the FGQCs and heptoma cell line smmc-7721 cells was observed for the first time by TEM ultrathin section imaging. At an excitation wavelength of 365nm, the graphene-QDs exhibit a strong luminescence in aqueous environments. The loading content and entrapment efficiency of the FGQCs were 70% and 50%, respectively. The cytotoxicity of this novel drug delivery system was evaluated in vitro using heptoma cell line smmc-7721 and quantified by the 3-(4,5-dimethylthiazol-z-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The results show that FGQCs are a promising new multifunctional material for drug delivery in biological and medical applications. Copyright 2013 Elsevier B.V. All rights reserved. 關(guān)鍵詞 關(guān)鍵詞列表:CdTe QDs; Drug delivery; Graphene cytotocity; Luminescence; Multifunctional 作者信息 地址:Materials Science and Engineering College, Guilin University of Technology, Guilin 541004, China; Ministry-Province Jointly-Constructed Cultivation Base for State Key Laboratory of Processing for Non-ferrous Metal and Featured Materials, Guangxi Zhuang Autonomous Region, Guilin, China. Electronic address: gloujun123@gmail.com. 文獻信息 文獻類型:Journal Article 語種:English PubMed ID:24373978 NLM 唯一 ID:9315133 創(chuàng)建日期: 30 Apr 2014 電子出版:11 Dec 2013 國家/地區(qū): Netherlands ISSN:1873-4367 其他信息 |
3樓2014-05-14 14:52:36
baiyuefei
版主 (文學(xué)泰斗)
風雪
- LS-EPI: 1647
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- 專業(yè): 合成藥物化學(xué)
- 管轄: 有機交流
【答案】應(yīng)助回帖
感謝參與，應(yīng)助指數(shù) +1
2樓2014-05-14 14:52:20
jiangyumin2
鐵桿木蟲 (著名寫手)
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4樓2014-05-14 15:10:13
jiangyumin2
鐵桿木蟲 (著名寫手)
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5樓2014-05-14 15:11:56
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