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佟玉風銀蟲 (著名寫手)
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[求助]
求翻譯一段中文摘要
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HPLC法分析在D-GlaN致急性肝損傷模型大鼠尿液中肋柱花化學成分 摘要：目的：研究肋柱花水煎液在D-GlaN致急性肝損傷模型大鼠尿液中的化學成分。方法：采用腹腔注射D-GlaN制備急性肝損傷大鼠模型；利用HPLC法對大鼠灌胃肋柱花水煎液后尿液中化學成分進行分析，檢測波長280nm；流動相為甲醇：水；流速1.0ml/min；柱溫35℃；梯度洗脫。結果：在含藥尿液中共標識25個峰，3個為藥物原型成分，10個為代謝產(chǎn)物；其余為尿液內(nèi)源性成分。 結論：該方法較全面的分析肋柱花在急性肝損傷模型大鼠尿液中的化學成分，為進一步研究肋柱花藥效物質(zhì)基礎提供依據(jù)。 關鍵詞：肋柱花；D-GlaN；急性肝損傷模型；尿液；HPLC |
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佟玉風
銀蟲 (著名寫手)
- 應助: 2 (幼兒園)
- 金幣: 1090.3
- 散金: 120
- 紅花: 6
- 帖子: 1031
- 在線: 41.4小時
- 蟲號: 3267129
- 注冊: 2014-06-10
- 性別: MM
- 專業(yè): 民族藥學
6樓2014-07-10 09:21:33
【答案】應助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★
RXMCDM: 金幣+1, 多謝應助！ 2014-07-09 07:28:27
佟玉風: 金幣+50, 翻譯EPI+1, ★★★很有幫助 2014-07-09 09:00:58
RXMCDM: 金幣+1, 多謝應助！ 2014-07-09 07:28:27
佟玉風: 金幣+50, 翻譯EPI+1, ★★★很有幫助 2014-07-09 09:00:58
abstract:purpose:To study the chemical compositions of Lomatogonium rotatum"s water decoction in the urine of the model rat which was induced acute liver damage by D-GlaN. Method:The model rats were injected by adominal injection of D-GlaN to gain acute liver damage.The chemical compositions in the urine of model rats which were fed Lomatogonium rotatum's water decoction have been analyzed the method of HPLC.The detection wavelength was 280nm.The mobile phase are methanol and water，F(xiàn)low rate was 1.0ml/min，The column temperature is 35 ℃，Gradient elution，The results， 25 peaks were found in the drug-containing urine. three original ingredients of drug,ten metabolites,the remaining components were the urine-derived ingredients. conclusion: The chemical compositions of Lomatogonium rotatum's water decoction in the urine of the model rat have been analyzed more comprehensive by this method,this method have provided the basis to further study Lomatogonium rotatum.僅供參考 |
2樓2014-07-08 19:21:14
佟玉風
銀蟲 (著名寫手)
- 應助: 2 (幼兒園)
- 金幣: 1090.3
- 散金: 120
- 紅花: 6
- 帖子: 1031
- 在線: 41.4小時
- 蟲號: 3267129
- 注冊: 2014-06-10
- 性別: MM
- 專業(yè): 民族藥學
3樓2014-07-09 08:28:20
4樓2014-07-09 08:36:13
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