 |
 |
 |
 |
 |
 |
||
 |
 |
 |
 |
 |
| 10 | 1/1 | 返回列表 |
| 查看: 1504 | 回復(fù): 9 | |||||
laozhuangzi銅蟲 (正式寫手)
|
[交流]
New Trends in Enzyme Catalysis and Biomimetic Chemical Reactions 已有3人參與
|
|
About two centuries ago the German poet, writer and philosopher J.W. Goethe noted that Nature is not only a great artist but also a skillful master. The contemporary generation of scientists who work in the fields of molecular biology, biochemistry and biophysics can appreciate to the fullest extent not only the internal beauty of natural molecular structures but also with what consummate skill these structures have been created. One of the wonderful creations of Nature, biological catalysis, appears as a challenging problem to chemists of the 21th century. The unique catalytic properties of enzyme, which are their precise specificity, selectivity, high rate of chemical reaction, and regulatory capacity occupy a great deal of attention. Classical and modern physical chemistry, chemical kinetics, organic, inorganic and quantum-chemistry provide an arsenal of physical methods and establish a basis for the investigation of structure and action mechanism of enzymes. The general properties of enzymes, the “ideal” chemical catalysts, are the formation of intermediates, smooth thermodynamic relief along the reaction coordinate, fulfillment of all selection rules for chemical reactions, the ability to proceed and to stop temporarily and spatially, and compatibility with the ambient media. These properties are possible by multifunctional active centers, by the unique structure of protein globules, possessing both rigidity and flexibility, and the formation of catalytic ensembles. Biochemistry returns to chemistry a plethora of knowledge about nearly “ideal” catalysts and opens the way for chemical modeling of enzyme reactions. This book is a view of enzyme catalysis by a physico-chemist with long-term experience in the investigation of structure and action mechanism of biological catalysts. This book is not intended to provide an exhaustive survey of each topic but rather a discussion of their theoretical and experimental background, and recent developments. The literature of enzyme catalysis is so vast and many scientists have made important contribution in the area, that it is impossible in the space allowed for this book to give a representative set of references. The author has tried to use reviews, and general principles of articles. He apologizes to those he has not been able to include. The first chapter of the present monograph expound upon new approaches and twists to traditional physical and kinetic methods of investigation of structure and action mechanism. The second chapter is a brief outline of current ideas on the general mechanisms of separate stages of enzyme catalytic processes. In the subsequent chapters, the author’s attention focuses on an analysis of structure and action mechanism of “tough” enzymatic processes which can not yet be effectively realized by chemists in ambient conditions: reduction of nitrogen, hydroxylation of alkans, conversion of light energy, photosynthetic water oxidation; etc. The present status of the knowledge of protein molecular dynamics (fluctuation dynamics of protein) and its paramount role in enzyme functions will be reviewed. Areas related to enzyme catalysis such as antibody catalysis, enzymes in organic solvents, enzymes in synthetic chemistry and enzyme design are outlined. In concluding chapter, a progress in chemical mimicking of “tough” enzymatic reactions is considered. |
回復(fù)此樓» 本帖附件資源列表
-
歡迎監(jiān)督和反饋：小木蟲僅提供交流平臺(tái)，不對(duì)該內(nèi)容負(fù)責(zé)。
本內(nèi)容由用戶自主發(fā)布，如果其內(nèi)容涉及到知識(shí)產(chǎn)權(quán)問題，其責(zé)任在于用戶本人，如對(duì)版權(quán)有異議，請(qǐng)聯(lián)系郵箱：xiaomuchong@tal.com - 附件 1 : New_Trends_in_Enzyme_Cata(BookZZ.org).pdf
2014-07-15 16:16:39, 4.3 M
» 收錄本帖的淘帖專輯推薦
 專業(yè)電子書 | 生物化學(xué)和分子生物學(xué) |
» 本帖已獲得的紅花（最新10朵）
louiexp» 猜你喜歡
307求調(diào)劑
已經(jīng)有9人回復(fù)
-
288求調(diào)劑
已經(jīng)有15人回復(fù)
-
085700資源與環(huán)境308求調(diào)劑
已經(jīng)有5人回復(fù)
-
294求調(diào)劑材料與化工專碩
已經(jīng)有14人回復(fù)
-
0817 化學(xué)工程 299分求調(diào)劑 有科研經(jīng)歷 有二區(qū)文章
已經(jīng)有18人回復(fù)
-
265求調(diào)劑
已經(jīng)有3人回復(fù)
-
296求調(diào)劑
已經(jīng)有6人回復(fù)
-
0703化學(xué)調(diào)劑
已經(jīng)有13人回復(fù)
-
085600材料與化工 求調(diào)劑
已經(jīng)有15人回復(fù)
-
生物學(xué)調(diào)劑招人！�。�
已經(jīng)有4人回復(fù)
0.8
| 頂一下，感謝分享！ |
2樓2014-07-15 18:18:02
0.8
| 頂一下，感謝分享！ |
3樓2014-07-16 22:26:20
0.8
| 頂一下，感謝分享！ |
4樓2014-07-17 03:47:11
 |
5樓2014-07-17 03:47:49
0.8
| 頂一下，感謝分享！ |
6樓2014-07-18 12:18:55
0.8
| 頂一下，感謝分享！ |
7樓2014-07-20 15:29:28
| 感謝分享 |
8樓2014-09-10 20:47:50
| 感謝分享!! |
9樓2014-10-28 17:19:03
louiexp
金蟲 (小有名氣)
- 應(yīng)助: 0 (幼兒園)
- 金幣: 605.5
- 帖子: 132
- 在線: 212.7小時(shí)
- 蟲號(hào): 1043041
- 注冊(cè): 2010-06-17
- 專業(yè): 生物無機(jī)化學(xué)
10樓2018-04-26 20:29:17
相關(guān)版塊跳轉(zhuǎn)
我要訂閱樓主 laozhuangzi 的主題更新
| 10 | 1/1 | 返回列表 |
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 生物學(xué)調(diào)劑招人�。�！ +3 | 山海天嵐 2026-03-17 | 4/200 |
|
|---|---|---|---|---|
|
|
[考研] 一志愿吉林大學(xué)材料學(xué)碩321求調(diào)劑 +7 | Ymlll 2026-03-18 | 10/500 |
|
|
|
[考研] 一志愿南京理工大學(xué)085701資源與環(huán)境302分求調(diào)劑 +3 | 葵梓衛(wèi)隊(duì) 2026-03-18 | 5/250 |
|
|
[考研] 304求調(diào)劑 +3 | 曼殊2266 2026-03-18 | 3/150 |
|
|
|
[考研] 0703化學(xué)調(diào)劑 +5 | pupcoco 2026-03-17 | 8/400 |
|
|
|
[考研] 0817調(diào)劑 +3 | 沒有答案_ 2026-03-14 | 3/150 |
|
|
|
[考研] 312求調(diào)劑 +8 | 陌宸希 2026-03-16 | 9/450 |
|
|
|
[考研] 0703化學(xué)調(diào)劑 +3 | 妮妮ninicgb 2026-03-17 | 3/150 |
|
|
|
[考博] 26博士申請(qǐng) +3 | 1042136743 2026-03-17 | 3/150 |
|
|
|
[考研] 考研求調(diào)劑 +3 | 橘頌. 2026-03-17 | 4/200 |
|
|
|
[考研] 326求調(diào)劑 +5 | 上岸的小葡 2026-03-15 | 6/300 |
|
|
|
[考研] 材料工程專碩274一志愿211求調(diào)劑 +6 | 薛云鵬 2026-03-15 | 6/300 |
|
|
|
[考研] 304求調(diào)劑 +4 | ahbd 2026-03-14 | 4/200 |
|
|
|
[考研] 318求調(diào)劑 +3 | Yanyali 2026-03-15 | 3/150 |
|
|
|
[考研] 321求調(diào)劑 +5 | 大米飯！ 2026-03-15 | 5/250 |
|
|
|
[考研] 0703 物理化學(xué)調(diào)劑 +3 | 我可以上岸的對(duì)?/a> 2026-03-13 | 5/250 |
|
|
|
[考研] 0856求調(diào)劑 +3 | 劉夢(mèng)微 2026-03-15 | 3/150 |
|
|
|
[考研] 中科大材料與化工319求調(diào)劑 +3 | 孟鑫材料 2026-03-14 | 3/150 |
|
|
|
[考研] 材料與化工 323 英一+數(shù)二+物化，一志愿：哈工大 本人本科雙一流 +4 | 自由的_飛翔 2026-03-13 | 5/250 |
|
|
|
[考研] 311求調(diào)劑 +3 | 冬十三 2026-03-13 | 3/150 |
|