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[資源]
《創(chuàng)新藥物化學(xué)》英文原版下載
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在壇子里看到Jamma兄弟關(guān)于遲玉明主譯的《創(chuàng)新藥物化學(xué)》中文版的帖子，如下 http://www.dxy.cn/bbs/post/view? ... amp;tpg=1&age=0 我看過一部分，感覺英文原版的更為地道。這個(gè)有朋友也提到過，說在譯文中有錯(cuò)誤存在。有的朋友也希望能有人共享。 正好手中有英文原版紙版，書名為Practice of Medicinal Chemistry，第二版。于是，哥幾個(gè)熬通宵，把幾百頁的英文紙版掃描成PDF文檔，有70多MB，上傳給大家共享。 該書被譽(yù)為藥物化學(xué)方面的權(quán)威書籍，相信大家一定會(huì)受益匪淺。 很辛苦的掃描、上傳，其中艱辛不為人道。如果只下載不頂貼，兄弟會(huì)寒心的！ 原書信息如下： 書名 Practice of Medicinal Chemistry, 2nd ed ISBN-10 0-12-744481-5 作者 C. Wermuth, ed. 出版社 Academic Press, 2003, 624 pp., hard cover 目錄 A Brief History Of Drugs; From Plant Extracts To DNA Technology. Medicinal Chemistry: Definition And Objectives, The Three Main Phases Of Drug Activity, Drug And Diseases Classifications. Measurement And Expression Of Drug Effects. Drug Targets: Molecular Mechanisms Of Drug Action. Strategies In The Search For New Lead Compounds Or Original Working Hypotheses. Natural Products As Pharmaceuticals And Sources For Lead Structures. Basics Of Combinatorial Chemistry. The Contribution Of Molecular Biology To Drug Discovery. Electronic Screening: Lead Finding From Database Mining. High-Speed Chemistry Libraries: Assessment Of Drug-Likeness. Web Alert - Using The Internet For Medicinal Chemistry. Molecular Variations In Homologous Series: Vinylogues And Benzologues. Molecular Variations Based On Isosteric Replacements. Ring Transformations. Introduction Of Conformational Restriction And/Or Steric Hindrance. Identical And Non Identical Twin Drugs. Optical Isomerism In Drugs. Application Strategies For The Primary Structure-Activity Relationship Exploration. Specific Substituent Groups. The Role Of Functional Groups In Drug–Receptor Interactions. Compound Properties And Drug Quality. Quantitative Approaches To Structure-Activity Relationships. Structural Aspects Of Drug Action I. Pharmacophore Identification And Receptor Mapping. Three-Dimentional Quantitative Structure-Property Relationships. Protein Crystallography And Drug Discovery. Protein Comparative Modelling And Drug Discovery. The Transition From Agonist To Antagonist Activity: Symmetry And Other Considerations. Design Of Peptidomimetics. The Fate Of Xenobiotics In Living Organisms. Biotransformation Reactions. Chemical Mechanisms Of Toxicity. Basic Knowledge For Designing Safer Drugs. Designing Prodrugs And Bioprecursors. Macromolecular Carriers For Drug Targeting. Preparation Of Water Soluble Compounds Through Salt Formation. Preparation Of Water-Soluble Compounds By Covalent Attachment Of Solubilizing Moieties. Drug Solubilization With Organic Solvents, Surfactants And Lipids. Improvement Of Drug Properties By Cyclodextrins. Chemical And Physicochemical Solutions To Formulation Problems. Discover A Drug Substance, Formulate And Develop It To A Product. Drug Nomenclature. Legal Aspects Of Product Protection. The Consumption And Production Of Pharmaceuticals. 參考 http://www.sigmaaldrich.com/cata ... 819&Brand=SIGMA 最初申請(qǐng)了一些免費(fèi)的服務(wù)器用來和大家共享資源，但是國內(nèi)的資源很不穩(wěn)定，申請(qǐng)的服務(wù)器也失效了。讓我很無奈。 但是大家確實(shí)需要這本書，我再申請(qǐng)一個(gè)，然后把這本書再發(fā)一遍。 這次上傳的不是我們的掃描版，而是本人從網(wǎng)上找到的可編輯版本，分為兩個(gè)部分，下載后解壓即可。 下載鏈接： http://www.box.net/shared/1ic5u99s88 http://www.box.net/shared/10p000nsws |
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