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guozhaohui金蟲(chóng) (初入文壇)
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| 對(duì)D-青霉胺的合成進(jìn)行了研究.將青霉素G鉀鹽溶解于水中,再依次加入甲苯和冰醋酸,室溫下攪拌片刻后,加入苯胺,在氮?dú)獗Wo(hù)下,加熱回流5h,一步反應(yīng)生成了D-青霉胺.所得的產(chǎn)品結(jié)構(gòu)由核磁共振譜和比旋光度確認(rèn),D-青霉胺的產(chǎn)率為64%. |
金蟲(chóng) (初入文壇)
銅蟲(chóng) (初入文壇)
| we studied D - penicillamine synthesis .first, penicillin G potassium dissolved in water. adding toluene and glacial acetic acid in turn and stirring at room temperature for a brief moment. adding the aniline under protect of nitrogen ,then heating reflux 5 h, we get D - penicillamine after one step. The product structure is affirmed by nuclear magnetic resonance (NMR) spectroscopy and optical rotation, and the yield of D - penicillamine is 64%. |
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