Silica-based nanocapsules: synthesis, structure control and biomedical applications
Yu Zhang,a Benedict You Wei Hsu,b Changliang Ren,c Xu Li*c and John Wang*ab
硅基納米膠囊的合成、結(jié)構(gòu)及生物醫(yī)學(xué)應(yīng)用(21頁(yè)87篇文獻(xiàn))
Synergistically combining the merits of silica (e.g., mechanical robustness, biocompatibility and great versatility in surface functionalization) and capsular configurations (e.g., a large inner cavity, low density and favourable
colloidal properties), silica-based nanocapsules (SNCs) with a size cutoff of B100 nm have gained growing interest in encapsulating bioactive molecules for bioimaging and controlled delivery applications. Within this context, this review provides a comprehensive overview of the synthetic strategies, structural control and biomedical applications of SNCs. Special emphasis is placed on size control at the nanoscale and material composition manipulation of each strategy and the newly emerging synthetic strategies. The applications of SNCs in bioimaging/diagnosis and drug delivery/therapy and the structure engineering that is critically important for the bio-performance of SNCs are also addressed in this review.
通訊作者之一
1 Introduction![Chem Soc Rev10.13新鮮在線:Silica-based nanocapsules]()
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