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| β-cyclodextrin (β-CD), a cyclic oligosaccharide composed of seven glucose molecules with -1,4-glucosidase linkages, is produced from amylose by cyclodextrin glucosyltransferase from Bacillus, which has a micro-environment of a chiral, hydrophilic outside and a hydrophobic interior cavity (Szejtli, 1998; Dell Valle, 2004). Previous studies have focused on the use of theβ-CD structure in forming inclusion compounds that are mainly used for organic compound adsorption and applications in fields dealing with environmental protection, cosmetics, slow-release drugs, and so on (Banerjee & Chen, 2010; Cobos, Martinez Perez, Monreal Romero, & Garcia Casillas, 2007; Guo & Jiang, 2007). β-CD is biodegradable and contains a number of alcoholic hydroxyl groups for chemical reactions such as etherification, esterification, oxidation, cross-linking, and so on (Dell Valle, 2004). β-CD is suitable as starting material for the synthesis of SAP due to the abundant hydrophilic hydroxyl group. However, the molecular weight of β- CD is low. In order to increase molecular weight of the product, hydrophilic monomer could be link with β-CD by chemical crosslinking reactions. Meanwhile, the cyclic oligosaccharide chemical structure of β-CD could increase three-dimensional network structure of product in cross-linking reactions, favoring the swelling capacity of the product. |
至尊木蟲 (知名作家)
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| β環(huán)糊精(β-CD)為一環(huán)狀寡糖,由7個葡萄糖分子通過α-1,4-葡糖苷鍵連接組成,在芽孢桿菌環(huán)糊精葡糖基轉(zhuǎn)移酶作用下由直鏈淀粉生成,具有一個手性、親水性的外層和疏水性內(nèi)部空腔微環(huán)境(Szejtli, 1998; Dell Valle, 2004)。以前的研究集中在利用β-CD結(jié)構(gòu)形成包合物,主要用于有機化合物的吸附和環(huán)保處理,化妝品,緩釋藥物等領域(Banerjee & Chen, 2010; Cobos, Martinez Perez, Monreal Romero, & Garcia Casillas, 2007; Guo & Jiang, 2007)。 β-CD是可生物降解的,含有大量醇羥基以便進行醚化,酯化,氧化,交聯(lián),等化學反應(Dell Valle,2004)。由于含有大量的親水性羥基,β-CD適合作為用于合成SAP的起始材料。然而,β-CD的分子量低。為了提高產(chǎn)物的分子量,親水性單體可以通過化學交聯(lián)反應與β-CD鏈接。同時,β-CD的環(huán)狀寡糖化學結(jié)構(gòu)可以提高交聯(lián)反應產(chǎn)物的三維網(wǎng)狀結(jié)構(gòu),有利于產(chǎn)物的溶脹能力。 |
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