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各位高手,我投了一篇文章,審稿意見給了一句:Throughout the study, please clarify whether the number of zinc ions bound to the six zinc finger proteins of MTF-1 changes, rather than the number of zinc finger proteins themselves.- this was only done in the abstract 請大家看看我的摘要哪里需要改動(dòng),怎么改?本人英語不好 摘要: Metal ion homeostasis and heavy metal detoxifica- tion systems are regulated by certain genes associated with metal ion transport. Metallothionein (MT) and metal response element binding transcription factor 1 (MTF-1) are important regulatory proteins involved in the mediation of intracellular metal ion balance. Differences in the zinc-binding affinities of the zinc fingers of MTF-1 and the α- and β-domains of MT facilitate their regulation of Zn2+ concentration. Alterations in the intracellular concentration of Zn2+ influence the MTF-1 zinc finger number, and MTF-1 containing certain zinc finger numbers regulates the expression of corresponding target genes. The present review evaluates the association between zinc finger number in MTF‑1 protein, MTF-1 target genes and the mechanism underlying MT regulation of the zinc finger number in MTF-1. |

至尊木蟲 (職業(yè)作家)

榮譽(yù)版主 (文壇精英)
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你在摘要中提到了【Differences in the zinc-binding affinities of the zinc fingers of MTF-1】 and the α- and β-domains of MT facilitate their regulation of Zn2+ concentration. Alterations in the intracellular concentration of Zn2+ influence the MTF-1 zinc finger number, and MTF-1 containing certain zinc finger numbers regulates the expression of corresponding target genes. 編輯讓你澄清問題,是Zn離子結(jié)合數(shù)量而不是鋅指蛋白數(shù)量發(fā)生了變化,摘要里面說明了,文中沒有,確認(rèn)一下 |
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