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3.3. SEM micrographs of PLGA/PHBV scaffold The morphology of the pure PLGA scaffold and PLGA/PHBV scaffolds containing different amount of PHBV microspheres were shown in Fig. 3. The SEM graphs (A, B, C and D) showed the bonding between PHBV microspheres and PLGA matrix. The PHBV microspheres were distributed all across the PLGA matrix and most of them were buried in the PLGA matrix which might make them hard to separate from the matrix. Graphs A, C and E demonstrated that all of the three kinds of scaffold possessed interconnected porous structure. It can be observed from graphs A and C that the addition of PHBV microspheres made the morphology of the PLGA/PHBV scaffold much rougher than that of pure PLGA scaffold. However, with the increase of PHBV microspheres, the pore size of PLGA/PHBV scaffolds changed little. The PLGA matrix walls were decorated with PHBV microspheres which can be seen from graphs B and D and they were seldom influenced by PHBV microspheres, which can be convinced by the well-connected walls. |
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| 純PLGA骨架和含有不同量PHBV微球的PLGA / PHBV支架的形態(tài)如圖3所示。SEM譜圖(A,B,C和D)顯示了PHBV微球和PLGA基質(zhì)間的連接。PHBV微球分布遍及整個PLGA基質(zhì),其中大部分被掩埋在PLGA基質(zhì),這可能使得他們難以從基質(zhì)中分離出來。圖A,C和E表明,這三種骨架都具有三維連通的多孔結(jié)構(gòu)。從曲線圖A和C可以看出,PHBV微球的加入使得PLGA / PHBV骨架比純PLGA骨架形態(tài)更粗糙。然而,隨著PHBV微球的增加, PLGA / PHBV骨架的孔徑變化不大。從曲線B和D可以看出,PLGA基質(zhì)壁上裝飾有PHBV微球,卻很少被PHBV微球影響,這一點可以從連通性好的基質(zhì)壁上得到證明。 |

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