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hanbing7525銀蟲 (小有名氣)
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[求助]
英譯漢，，，，在線急等！�。。。。。。�！
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Native C3 itself is biologically inactive. C3 is derived by proteolytic processing of a single-chain proC3 precursor to and -chains (Fig. 1A). C3 contains eight MG (macroglobulin) domains that form a key ring, with MG1–4 completing one ring,MG5 and MG6 forming a second, overlapping half-ring, and MG7 and MG8 extending the second half-ring . The C345C domain forms a knob-like protrusion (Fig. 1B). The TED is inserted in the CUB domain, which in turn is inserted between MG domains 7 and 8 (Fig. 1 A and B). The reactive thioester bond is shielded from solvent within the interface of the TED with the MG8 domain (Fig. 1B). EM revealed three different groups (I–III) of C3 class averages with different orientations on the grid (Fig. 2 A Lower), which show excellent cross-correlation with projections from the crystal structure (Fig. 3 A–C). The domains in C3 are most clearly visible in the group II orientation (Fig. 3B, compare with Fig. 1B). |
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weichao123
金蟲 (小有名氣)
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【答案】應(yīng)助回帖
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愛與雨下: 金幣+1 2015-01-02 09:27:53
hanbing7525(RXMCDM代發(fā)): 金幣+40, 多謝應(yīng)應(yīng)助！ 2015-02-01 08:56:26
RXMCDM: 翻譯EPI+1 2015-02-01 08:56:32
愛與雨下: 金幣+1 2015-01-02 09:27:53
hanbing7525(RXMCDM代發(fā)): 金幣+40, 多謝應(yīng)應(yīng)助！ 2015-02-01 08:56:26
RXMCDM: 翻譯EPI+1 2015-02-01 08:56:32
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???C3???????????????? C3?????????PROC3??????????????-chains ???1A?????á? C3???????MG???????? ?γ????????????MG1a ? ??4?????????? MG5??MG6?γ????????????? MG7??MG8??????????? ????C345C???γ????????????1B?? ????TED????CUB????????????MG??7??8 ???1 A??B??????????????????????????ε?TED??MG8???1B?????????? EM?????????????????C3????????????????????2?????????????????????????????????????????????? ???3??AA ???IA ? ?????C ?? ????C3?е???????????????????????????3B?У???????1B?? ?? |
3樓2014-12-31 15:26:14
【答案】應(yīng)助回帖
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愛與雨下: 金幣+1 2015-01-02 09:28:04
hanbing7525(RXMCDM代發(fā)): 金幣+10, 多謝應(yīng)助！ 2015-02-01 08:56:07
愛與雨下: 金幣+1 2015-01-02 09:28:04
hanbing7525(RXMCDM代發(fā)): 金幣+10, 多謝應(yīng)助！ 2015-02-01 08:56:07
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原始的C3無生物活性。C3由proC3單鏈前驅(qū)體水解為多連時得到（圖1A）。C3含八個巨球蛋白，形成了鑰匙鏈，其中MG1–4為一環(huán)、MG5及MG6為重疊第二環(huán)，而MG7及MG8重疊為另半環(huán)。C345C域形成了瘤狀突起。（圖1B） 將TED插入CUB域中，而CUB則插入于MG域7與8之間（圖1A及1B）。將活性硫脂鏈與TED及MG8界面中的溶劑相隔離（圖1B）。 （翻譯了一部分，太專業(yè)了，不知道你們的"行話"   |
2樓2014-12-19 11:05:33
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