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taiyang0209銀蟲 (小有名氣)
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[求助]
審稿意見,不是太理解,求指點(diǎn) 已有1人參與
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剛收到一篇論文的審稿意見,有一條不是很清楚,理解不透,希望大家?guī)兔χ更c(diǎn)一下 Since the authors used a high sensitivity and mass accuracy analytical tool to quantify the drug metabolites, UPLC-QTOF system, the authors should fully use the advantage of the system by using its selective ion monitoring feature to detect the metabolites with pair of transition ion (parent ion and its characteristic ion) for drug 1 and drug 2. I noticed that the authors did mention the use of MSn scan function to detect the precursor ion and fragment ion in a single run, but the data was likely not used for the validation study. This is because only extracted ion chromatograms from mass screening as Figure 1 and Figure 2 were included in the results and discussion. 圖一和圖二只給出了EIC,這個(gè)審稿人的意思是在validation中要給出什么呢?或者是要做什么呢?不是很明白他說的意思,麻煩大家?guī)兔忉屢幌,謝謝 |
銀蟲 (小有名氣)
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