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[求助]
I型AAA蛋白家族和II型AAA蛋白家族的區(qū)別
最近在寫一篇關(guān)于CDC48的論文,再看文獻(xiàn)的過程中發(fā)現(xiàn)一些文獻(xiàn)提出CDC48屬于II型AAA家族,因?yàn)槠浜袃蓚(gè)ATP酶結(jié)構(gòu)區(qū),但是之前看過一篇文獻(xiàn),講的是II型AAA家族含有一個(gè)ATP酶結(jié)構(gòu)區(qū)( The superfamilycan be divided into two distinct classes, based solelyon the number of AAA domains (or NBDs) present in the protein [6]. Class I proteins (e.g. ClpA, ClpB, ClpC and ClpE) contain two highlyconserved NBDs, referred to as AAA-1 (or D1) and AAA-2 (or D2), separated bya linker sequence (or middle region) of variable length. In contrast, class II proteins (e.g. ClpX and HslU(ClpY)) contain onlya single NBD (homologous to D2).),(來源于文獻(xiàn):AAA+ proteins and substrate recognition, it all depends on their partner in crime)另一文獻(xiàn)中的圖也是這么標(biāo)注的,F(xiàn)在比較暈。請問是我對這段話的理解有錯(cuò)誤還是標(biāo)準(zhǔn)有所改變?希望各位大俠幫忙分析一下,到底應(yīng)該是那種類型的AAA家族!
![I型AAA蛋白家族和II型AAA蛋白家族的區(qū)別]()
AAA結(jié)構(gòu)域.jpg |
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