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Malyhon新蟲 (小有名氣)
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[求助]
幾句論文求大神翻譯成中文 謝謝
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Upon grafting RGD peptides to the PHBV-PEGMAL surface, the adsorbed amount of serum decreases to 73(6ng/cm2 on the PHBV-RGDsurface becauseRGDpeptides bind to the activemaleimide groups. The amount of adsorbed serum decreases by 50% compared with that on the unmodified surface. Moreover, the fact that PEG chains with a molecular weight of 2.3 kDa have a better protein resistance in our system than those with a molecular weight of 5 kDa, likely because of the larger steric hindrance from longer chains, suggests that the choice of bifunctional PEG with a molecular weight of ∼2 kD should be more suitable in our system. The above results indicate that our modification method can effectively reduce the nonspecific protein adsorption from serum, which is favorably applied in tissue engineering. |
至尊木蟲 (著名寫手)
| 通過結(jié)合到活化馬來酰胺基團(tuán)導(dǎo)入RGD小肽到PHBV-PEGMAL表面之后,血清蛋白吸附量降低至73(單位, 6ng/cm2),比未修飾PHBV表面血清蛋白吸附量減少一半。再者,可能是由于高分子量PEG的空間位阻較高的緣故,在我們體系中分子量為2.3kDa的PEG比分子量為5kDa的PEG更具蛋白排斥效果,選擇MW大約2KD的PEG更合適。上述結(jié)果表明我們的修飾方法可以有效地減少血清蛋白的非專一吸附,可以適用于組織工程應(yīng)用中。 |

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