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To avoid the possible chain relaxation processes, bifunctional PEG should be linked to PHBV-NH2 surfaces through the reaction between the amino groups and the hydroxysuccinimidyl groups, immediately after NH3 plasma treatment. The contact angle of the resulting film was 35(2, consistent with PEG films reported in the literature.38 Finally, RGD peptides were grafted and the contact angle rose to 45(1 because of the hydrophobic groups of the introduced peptides.39 Such a surface modification strategy renders the PHBV surface hydrophilicity through the NH3 plasma treatment and the introduction of PEG segments. In general, the hydrophilic surface property is helpful to improve the material’s biocompatibility |
金蟲 (著名寫手)
| 為了避免這種潛在的鏈松弛過程,雙官能的PEG應(yīng)該在NH3血漿治療之后立即通過氨基和羥基琥珀酰亞胺基團之間的反應(yīng)而連接到PHBV-NH2表面。 形成的膜的接觸角為35 ( 2,與文獻報導(dǎo)的PEG膜一致。38最后,RGD縮氨酸被接枝,接觸角達到45 (1這是因為引入的縮氨酸的疏水基的關(guān)系。39這種表面改性策略通過NH3血漿治療和引入PEG片段而呈現(xiàn)出這種PHBV表面親水性。一般說來,這種親水表面性質(zhì)有助于改善這種材料的生物適合性 |
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