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ykd321銅蟲 (初入文壇)
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[求助]
求摘要翻譯！
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摘要：采用乙醇注入法制備尼群地平脂質(zhì)體。以包封率為考察指標(biāo)，對影響尼群地平脂質(zhì)體包封率的因素卵磷脂的量、膽固醇的量與攪拌水化時間三個因素進行考察，采用正交設(shè)計對尼群地平脂質(zhì)體的制備工藝進行優(yōu)化，以確定最佳制備工藝。最佳制備工藝下制得的脂質(zhì)體加入凍干保護劑后于冰箱中-20℃條件下冷凍24h，再于-50℃條件下真空冷凍干燥12h得到凍干粉針。 關(guān)鍵詞：乙醇注入法；尼群地平；包封率；正交設(shè)計；真空冷凍干燥 |
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genhunter
至尊木蟲 (著名寫手)
- 翻譯EPI: 387
- 應(yīng)助: 259 (大學(xué)生)
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- 在線: 1793小時
- 蟲號: 2558361
- 注冊: 2013-07-22
- 專業(yè): 腫瘤化學(xué)藥物治療
【答案】應(yīng)助回帖
| Abstract: Liposomal nitrendipine was prepared by ethanol injection method. Using encapsulation rate as an indicator, the following three factors, the amount of phosphotidylcholine, the amount of cholesterol and stirring-hydration time, were evaluated to determine the influence on the liposome encapsulation rate of nitrendipine. The liposome preparation method was optimized based on an orthogonal design to determine the best preparation process. The liposomes prepared under optimized condition were added with cryo-protectant, and frozen in a refrigerator at - 20 ℃ for 24 h, then lyophilized for 12 hrs under - 50 ℃ to produce freeze-dried powder for injection. |
2樓2015-05-17 22:54:56
genhunter
至尊木蟲 (著名寫手)
- 翻譯EPI: 387
- 應(yīng)助: 259 (大學(xué)生)
- 金幣: 9757.4
- 散金: 10
- 紅花: 60
- 帖子: 2484
- 在線: 1793小時
- 蟲號: 2558361
- 注冊: 2013-07-22
- 專業(yè): 腫瘤化學(xué)藥物治療
3樓2015-05-18 08:45:07
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