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sapphires008鐵桿木蟲 (著名寫手)
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[求助]
請(qǐng)幫我查下web of science 是否能檢索到這篇文章，pubmed上已經(jīng)可以檢索到
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請(qǐng)幫我查下web of science 是否能檢索到這篇文章，pubmed上已經(jīng)可以檢索到： Lei F, Gao Y, Liu F, Hou R, Cai RL, and Qi Y. Shuang-Huang-Lian Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Mice Involving Anti-Inflammatory and Antioxidative Activities. Evid Based Complement Alternat Med, 2015, doi: 10.1155/2015/283939. 謝謝！ |
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Shuang-huang-lian attenuates lipopolysaccharide-induced acute lung injury in mice involving anti-inflammatory and antioxidative activities. 作者:Fang, Lei; Gao, Yuan; Liu, Fen; Hou, Rui; Cai, Run-Lan; Qi, Yun Evidence-based complementary and alternative medicine : eCAM 卷:2015 頁:283939 DOI:10.1155/2015/283939 出版年:2015 (Epub 2015 Apr 06) 摘要 Shuang-Huang-Lian (SHL) is a common traditional Chinese preparation extracted from Lonicerae Japonicae Flos, Scutellariae Radix, and Fructus Forsythiae. In this study, we demonstrate the anti-inflammatory and antioxidative effects of SHL on lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in mice. SHL reduced the lung wet/dry weight ratio, lowered the number of total cells in the bronchoalveolar lavage fluid, and decreased the myeloperoxidase activity in lung tissues 6h after LPS treatment. It also inhibited the overproduction of proinflammatory cytokines (TNF-alpha, IL-1beta, and IL-6) in the bronchoalveolar lavage fluid. Histological studies demonstrated that SHL attenuated LPS-induced interstitial edema, hemorrhage, and the infiltration of neutrophils into the lung tissue. Moreover, SHL could also enhance the superoxide dismutase and catalase activities, increase the reduced glutathione content, and decrease the malondialdehyde content. The present results suggest that SHL possesses anti-inflammatory and antioxidative properties that may protect mice against LPS-induced ALI. 作者信息 地址:Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China. 文獻(xiàn)信息 文獻(xiàn)類型:Journal Article 語種:English PubMed ID:25945107 NLM 唯一 ID:101215021 創(chuàng)建日期: 06 May 2015 完成日期: 06 May 2015 修訂日期: 08 May 2015 電子出版:06 Apr 2015 國(guó)家/地區(qū): United States ISSN:1741-427X 期刊信息 Impact Factor (影響因子): Journal Citation Reports® 其他信息 記錄所有者:NLM 狀態(tài)  ubMed-not-MEDLINE |
2樓2015-06-10 22:32:22
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